A One-Pot Synthesis of 1,4-dihydropyrimido[1,2-a] benzimidazoles and their Antimicrobial Activity

Authors

  • Kalpesh V. Vilapara  Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India
  • Rajendra M. Jadav  Department of chemistry, Bhavan’ssheth R. A. college of science, Ahmedabad, Gujarat, India
  • Sagar P. Gami  Department of chemistry, Bhavan’ssheth R. A. college of science, Ahmedabad, Gujarat, India

Keywords:

Pyrimidine, Benzimidazole, Cyclocondensation, Antimicrobial

Abstract

A one-pot synthesis of 1,4-dihydropyrimido[1,2-a]benzimidazole were carried out by Biginelli like cyclocondensation of aromatic aldehydes and acetoacetic acid derivatives with 2-amino benzimidazole containing a guanidine fragment. The newly synthesized compounds were characterized by IR, NMR and Mass spectroscopy.

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International Journal of Scientific Research in Science and Technology

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Published

2018-02-28

Issue

Volume 3, Issue 7, September-October-2017

Section

Research Articles

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How to Cite

[1]
Kalpesh V. Vilapara, Rajendra M. Jadav, Sagar P. Gami, " A One-Pot Synthesis of 1,4-dihydropyrimido[1,2-a] benzimidazoles and their Antimicrobial Activity, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 7, pp.1204-1210 , September-October-2017.