Larvicidal Effect of Seeds of Myristica Fragrans (Houttuyn) on Larvae of Anopheles Gambiae

Authors

  • Romanus Umoh  Department of Pharmacognosy and Natural Medicine, University of Uyo, Nigeria
  • Samuel Offor  Department of Pharmacognosy and Natural Medicine, University of Uyo, Nigeria
  • Nkechi Onyeukwu  Department of Pharmacology and Toxicology, University of Uyo, Nigeria
  • Akwaowo Elijah  Department of Biopharmacy and Clinical Pharmacy, University of Uyo, Nigeria
  • Hilary Otimanam  Department of Pharmacology and Toxicology, University of Uyo, Nigeria
  • Timma Uwah  Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Nigeria
  • Clement Jackson  Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Nigeria

Keywords:

Anopheles gambiae , Myristica fragrans, Larval toxicity, %mortality and  LC50

Abstract

The Larvicidal Activity of Methanol extract and fractions of Myristica fragrans (Myristicaceae) was evaluated on larvae of Anopheles gambiae. The seeds were macerated in 100% redistilled n-hexane for 24 hours to extract the oil, then in 100% redistilled methanol for 72hours, filtered and concentrated to dryness. The methanol crude extract of M. fragrans seeds exhibited % mortalities range of 30.00 + 0.00 -100+0.00 and LC50 of 0.02 mg/mL. N-hexane fraction of M. fragrans seeds was equally as active fraction with % mortalities range of 25+ 1.00-100+0.00 and LC50 of 0.02mg/mL. The reference compound Nicotine had %mortality range of 15.00+ 0.00 – 100.00+0.00 with LC50 of 0.04mg/mL.

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International Journal of Scientific Research in Science and Technology

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Published

2015-06-30

Issue

Volume 1, Issue 2, May-June-2015

Section

Research Articles

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How to Cite

[1]
Romanus Umoh, Samuel Offor, Nkechi Onyeukwu, Akwaowo Elijah, Hilary Otimanam, Timma Uwah, Clement Jackson, " Larvicidal Effect of Seeds of Myristica Fragrans (Houttuyn) on Larvae of Anopheles Gambiae, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 1, Issue 2, pp.42-46, May-June-2015.