Larvicidal Effect of Seeds of Myristica Fragrans (Houttuyn) on Larvae of Anopheles Gambiae

Authors(7) :-Romanus Umoh, Samuel Offor, Nkechi Onyeukwu, Akwaowo Elijah, Hilary Otimanam, Timma Uwah, Clement Jackson

The Larvicidal Activity of Methanol extract and fractions of Myristica fragrans (Myristicaceae) was evaluated on larvae of Anopheles gambiae. The seeds were macerated in 100% redistilled n-hexane for 24 hours to extract the oil, then in 100% redistilled methanol for 72hours, filtered and concentrated to dryness. The methanol crude extract of M. fragrans seeds exhibited % mortalities range of 30.00 + 0.00 -100+0.00 and LC50 of 0.02 mg/mL. N-hexane fraction of M. fragrans seeds was equally as active fraction with % mortalities range of 25+ 1.00-100+0.00 and LC50 of 0.02mg/mL. The reference compound Nicotine had %mortality range of 15.00+ 0.00 – 100.00+0.00 with LC50 of 0.04mg/mL.

Authors and Affiliations

Romanus Umoh
Department of Pharmacognosy and Natural Medicine, University of Uyo, Nigeria
Samuel Offor
Department of Pharmacognosy and Natural Medicine, University of Uyo, Nigeria
Nkechi Onyeukwu
Department of Pharmacology and Toxicology, University of Uyo, Nigeria
Akwaowo Elijah
Department of Biopharmacy and Clinical Pharmacy, University of Uyo, Nigeria
Hilary Otimanam
Department of Pharmacology and Toxicology, University of Uyo, Nigeria
Timma Uwah
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Nigeria
Clement Jackson
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Nigeria

Anopheles gambiae , Myristica fragrans, Larval toxicity, %mortality and  LC50

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Publication Details

Published in : Volume 1 | Issue 2 | May-June 2015
Date of Publication : 2015-06-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 42-46
Manuscript Number : IJSRST151216
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Romanus Umoh, Samuel Offor, Nkechi Onyeukwu, Akwaowo Elijah, Hilary Otimanam, Timma Uwah, Clement Jackson, " Larvicidal Effect of Seeds of Myristica Fragrans (Houttuyn) on Larvae of Anopheles Gambiae", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 1, Issue 2, pp.42-46, May-June-2015.
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