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Role of Biomarkers in Cancer Research and Drug Development

Authors(2) :-Mahin Ghorbani, Hamed karimi

Biomarkers as characterizing agents of patient colony and quantifying factors to a specific degree to which developing drugs reach the intended targets, induce alternation of proposed pathophysiological mechanism and obtain desirable clinical results. These specific molecular signatures have been emerged rapidly in cancer research and cancer related drug development programs and have been helped vigorously in validation of novel drug targets and prediction of drug response which together lead to precise and strong treatment of cancer diseases. In this paper we have discussed emergence of biomarkers in drug development linked to cancer treatment and highlighted their significant role in the mentioned area. The purpose of this review is to redefine the biomarker evolution in drug development related to different types of cancers and a brief background about their classification, their assessment and technologies used for their identification in order to encourage scientists for strong focus on biomarkers in their research programs related to cancer treatment. Several types of biomarkers are discussed in this paper are such as biomarkers for breast, prostate, colon, ovarian, lung, cervical cancers, hepatocellular carcinoma, nasopharyngeal carcinoma and myeloid leukaemia.
Mahin Ghorbani, Hamed karimi
Biomarkers, Cancer Research, Drug Development, Target Validation, Biomarker Classification
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Publication Details
  Published in : Volume 1 | Issue 3 | July-August 2015
  Date of Publication : 2015-08-25
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 127-132
Manuscript Number : IJSRST151324
Publisher : Technoscience Academy
PRINT ISSN : 2395-6011
ONLINE ISSN : 2395-602X
Cite This Article :
Mahin Ghorbani, Hamed karimi, "Role of Biomarkers in Cancer Research and Drug Development", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 1, Issue 3, pp.127-132, July-August-2015
URL : http://ijsrst.com/IJSRST151324