Role of Biomarkers in Cancer Research and Drug Development

Authors

  • Mahin Ghorbani  Department of Biotechnology, Fergusson College, F.C. Road, Pune, Maharashtra, India
  • Hamed karimi  Department of Information Technology, Payam Noor University of Farokh-shahr, Farokh-shahr, Chaharmahl va bakhtiari, Iran

Keywords:

Biomarkers, Cancer Research, Drug Development, Target Validation, Biomarker Classification

Abstract

Biomarkers as characterizing agents of patient colony and quantifying factors to a specific degree to which developing drugs reach the intended targets, induce alternation of proposed pathophysiological mechanism and obtain desirable clinical results. These specific molecular signatures have been emerged rapidly in cancer research and cancer related drug development programs and have been helped vigorously in validation of novel drug targets and prediction of drug response which together lead to precise and strong treatment of cancer diseases. In this paper we have discussed emergence of biomarkers in drug development linked to cancer treatment and highlighted their significant role in the mentioned area. The purpose of this review is to redefine the biomarker evolution in drug development related to different types of cancers and a brief background about their classification, their assessment and technologies used for their identification in order to encourage scientists for strong focus on biomarkers in their research programs related to cancer treatment. Several types of biomarkers are discussed in this paper are such as biomarkers for breast, prostate, colon, ovarian, lung, cervical cancers, hepatocellular carcinoma, nasopharyngeal carcinoma and myeloid leukaemia.

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International Journal of Scientific Research in Science and Technology

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Published

2015-08-25

Issue

Volume 1, Issue 3, July-August-2015

Section

Research Articles

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How to Cite

[1]
Mahin Ghorbani, Hamed karimi, " Role of Biomarkers in Cancer Research and Drug Development, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 1, Issue 3, pp.127-132, July-August-2015.