Antimicrobial, Antioxidant and Anti-Inflammatory Activities of the extract of a Moroccan endemic Narcissus: Narcissus broussonetii

Authors(12) :-Amal Razik, Farida ADLY, Mina MOUSSAID, Chadi BERHAL, Hassan MOUSSAID, Abdelaziz ELAMRANI, Touria Ould BELLAHCEN, Nourdinne BOURHIM, Jamal Jamal EDDINE, Carles CODINA, Jaume BASTIDA, Mohamed LOTFI

The antioxidant, antibacterial and anti-inflammatory activities, of the extract of the Narcissus broussonetii bulbs were studied. The report concerning those properties of this Moroccan endemic species is described for the first time. Nine main alkaloids compounds were identified by GC and GC-MS such as tazettine, pretazettine, homolycorine, lycorine, ismine, 3-epimacronine and papiramine. The extracts of N. broussonetii up to 40 mg/100g b.wt, revealed a significant anti-inflammatory effect in mice and showed also a significant scavenging activity at 10 mg mL-1. However, the extractshowed a moderate antibacterial activity against all the microorganisms tested.

Authors and Affiliations

Amal Razik
Laboratory of Biochemistry, Cellular and Molecular Biology, Faculty of Sciences, Casablanca, Morocco
Farida ADLY
Laboratory of Biochemistry, Cellular and Molecular Biology, Faculty of Sciences, Casablanca, Morocco
Mina MOUSSAID
Laboratory of Organic Synthesis and Biological Studies, Faculty of Sciences, Casablanca, Morocco
Chadi BERHAL
Laboratory phytosanitary Faculty of Agriculture, Beirut, Lebanon
Hassan MOUSSAID
Laboratory of Pharmaceutical Chemistry, Institute of Pharmacy, Brussels, Belgium
Abdelaziz ELAMRANI
Laboratory of synthesis, extraction, and Physico-chemical study of organic molecules, Faculty of Sciences Aînchock, Casablanca, Morocco
Touria Ould BELLAHCEN
Biology Department, Faculty of Sciences Ain-chock, Casablanca, Morocco
Nourdinne BOURHIM
Laboratory of Biochemistry, Cellular and Molecular Biology, Faculty of Sciences, Casablanca, Morocco
Jamal Jamal EDDINE
Laboratory of synthesis, extraction, and Physico-chemical study of organic molecules, Faculty of Sciences Aînchock, Casablanca, Morocco
Carles CODINA
Department of Natural Products, Plant Biology and Soil Science, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
Jaume BASTIDA
Department of Natural Products, Plant Biology and Soil Science, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
Mohamed LOTFI
Laboratory of Biochemistry, Cellular and Molecular Biology, Faculty of Sciences, Casablanca, Morocco

Amaryllidaceae, Narcissus broussonetii, alkaloids, pharmaceutical activities.

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Publication Details

Published in : Volume 2 | Issue 1 | January-February 2016
Date of Publication : 2016-02-25
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 06-11
Manuscript Number : IJSRST151549
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Amal Razik, Farida ADLY, Mina MOUSSAID, Chadi BERHAL, Hassan MOUSSAID, Abdelaziz ELAMRANI, Touria Ould BELLAHCEN, Nourdinne BOURHIM, Jamal Jamal EDDINE, Carles CODINA, Jaume BASTIDA, Mohamed LOTFI, " Antimicrobial, Antioxidant and Anti-Inflammatory Activities of the extract of a Moroccan endemic Narcissus: Narcissus broussonetii", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 2, Issue 1, pp.06-11, January-February-2016.
Journal URL : http://ijsrst.com/IJSRST151549

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