Synthetic Study on Chalcone and their Dihydropyrimidinone and Dihydropyrimidinethione Derivatives

Authors(3) :-Basavaiah Umesha, Sowbhagya, Yeriyur Basavaiah Basavaraju

A series of chalcones, dihydropyrimidinone and dihydropyrimidinethione derivatives were synthesized in good yields by Claisen Schmidt reaction of acetophenones with substituted aldehydes in the presence of sodium hydroxide in water-ethanol mixture followed by the condensation reaction of chalcones with urea and thiourea in ethanol respectively. The structures of the synthesized compounds were elucidated based on spectroscopic evidence.

Authors and Affiliations

Basavaiah Umesha
Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru, Karnataka, India
Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysuru, Karnataka, India
Yeriyur Basavaiah Basavaraju
Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru, Karnataka, India

Chalcone, Urea, Thiourea, Dihydropyrimidinone, Dihydropyrimidinethione.

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Publication Details

Published in : Volume 2 | Issue 3 | May-June 2016
Date of Publication : 2017-12-31
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 340-343
Manuscript Number : IJSRST162343
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Basavaiah Umesha, Sowbhagya, Yeriyur Basavaiah Basavaraju, " Synthetic Study on Chalcone and their Dihydropyrimidinone and Dihydropyrimidinethione Derivatives", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 2, Issue 3, pp.340-343, May-June-2016.
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