Spectrophotometric Determination of Some Organophosphorus Pesticides Based on Reaction With Cerium (IV) Sulfate

Authors(4) :-Abd El-Aziz B. Abd El-Aleem, Mamdouh R. Rezk, Shaban M. Khalile, Omneya K. El-Naggar

A simple and sensitive spectrophotometric method has been described for the assay of some organophosphorus pesticides , (diazinon, chlorpyrifos and temefos) either in pure form or in dosage forms. The proposed method was based on the oxidation of the studied pesticides by a known excess of cerium (IV) sulfate in acidic medium and estimating the unreacted oxidizing agent by adding a known amount of methyl orange in the same acid medium and measuring the absorbance of the resulted solution at λmax=508 nm. Different variables affecting the reaction were studied and optimized. Beer’s law is obeyed in the concentration range of 1-8 µg ml-1 for diazinon and chlorpyrifos and 2-15 µg ml-1 for temefos. The proposed method was applied successfully for determination of the examined pesticides either in pure or dosage forms with good precision. No interferences were observed from excipients and the results obtained were in good agreement with those obtained using reported methods.

Authors and Affiliations

Abd El-Aziz B. Abd El-Aleem
Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt
Mamdouh R. Rezk
Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt
Shaban M. Khalile
National Organization for Drug Control And Research (NODCAR), Giza, Egypt
Omneya K. El-Naggar
National Organization for Drug Control And Research (NODCAR), Giza, Egypt

Spectrophotometry; Diazinon; Chlorpyrifos; Temefos; Cerium Sulphate; Methyl Orange.

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Publication Details

Published in : Volume 2 | Issue 6 | November-December 2016
Date of Publication : 2016-12-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 79-86
Manuscript Number : IJSRST162586
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Abd El-Aziz B. Abd El-Aleem, Mamdouh R. Rezk, Shaban M. Khalile, Omneya K. El-Naggar, " Spectrophotometric Determination of Some Organophosphorus Pesticides Based on Reaction With Cerium (IV) Sulfate, International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 2, Issue 6 , pp.79-86, November-December-2016. Available at doi : 10.32628/IJSRST162586
Journal URL : http://ijsrst.com/IJSRST162586

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