Intrafamilial Spread of hepatitis B virus in Elfao Province-East of Sudan

Authors(4) :-Hamid Omer, Abdel Rahim M. El Hussein, Khalid A Enan, Isam M. Elkhidir

The aim of the present study was to determine the intrafamilial spread of HBV in the family members of patients with Hepatitis B in Elfao Province, North of Sudan. In a descriptive-comparative study, 140 persons of 32 families of patients who were positive to Hepatitis B for more than 6 months and considered as index cases and 5250 first time blood donors (all males) in the same area were used as a control group were enrolled. Blood samples were taken from the participants and were checked for HBs Ag and HBC Ab. A total of 140 individuals, including 24 fathers and 24 mothers, 12 sisters,36 sons,18 daughters, 17 brothers, 2 uncle/son, 1uncle,1uncle/brother, 2 husbands,3 wives from 32 families were investigated. Out of the 140 subjects, (55.7%) were positive for HbsAg and (72.3%) were positive for anti-core. Among the control group (n: 5250), 206 subjects (3.9%) were HbsAg positive. The present survey indicates that there is a significant difference in the prevalence of Hepa¬titis B in the general population and family members of Hepatitis B patients and this is an evidence for horizontal transmission of HBV in household contacts.

Authors and Affiliations

Hamid Omer
Department of Medical microbiology, Faculty of Medical Laboratory Science, El Nellin University, Khartoum, Sudan
Abdel Rahim M. El Hussein
Department of Virology, Central Laboratory- The Ministry of Higher Education and Scientific Research, P.O. Box 7099,Khartoum, Sudan
Khalid A Enan
Department of Virology, Central Laboratory- The Ministry of Higher Education and Scientific Research, P.O. Box 7099,Khartoum, Sudan
Isam M. Elkhidir
Department of Microbiology and Parasitology, Faculty of Medicine, University of Khartoum, Khartoum, Sudan

Hepatitis B Virus, familial, Sudan.

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Publication Details

Published in : Volume 2 | Issue 6 | November-December 2016
Date of Publication : 2016-12-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 407-413
Manuscript Number : IJSRST162624
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Hamid Omer, Abdel Rahim M. El Hussein, Khalid A Enan, Isam M. Elkhidir, " Intrafamilial Spread of hepatitis B virus in Elfao Province-East of Sudan", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 2, Issue 6 , pp.407-413, November-December-2016.
Journal URL : http://ijsrst.com/IJSRST162624

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