Intrafamilial Spread of hepatitis B virus in Elfao Province-East of Sudan

Authors

  • Hamid Omer  Department of Medical microbiology, Faculty of Medical Laboratory Science, El Nellin University, Khartoum, Sudan
  • Abdel Rahim M. El Hussein  Department of Virology, Central Laboratory- The Ministry of Higher Education and Scientific Research, P.O. Box 7099,Khartoum, Sudan
  • Khalid A Enan  Department of Virology, Central Laboratory- The Ministry of Higher Education and Scientific Research, P.O. Box 7099,Khartoum, Sudan
  • Isam M. Elkhidir  Department of Microbiology and Parasitology, Faculty of Medicine, University of Khartoum, Khartoum, Sudan

Keywords:

Hepatitis B Virus, familial, Sudan.

Abstract

The aim of the present study was to determine the intrafamilial spread of HBV in the family members of patients with Hepatitis B in Elfao Province, North of Sudan. In a descriptive-comparative study, 140 persons of 32 families of patients who were positive to Hepatitis B for more than 6 months and considered as index cases and 5250 first time blood donors (all males) in the same area were used as a control group were enrolled. Blood samples were taken from the participants and were checked for HBs Ag and HBC Ab. A total of 140 individuals, including 24 fathers and 24 mothers, 12 sisters,36 sons,18 daughters, 17 brothers, 2 uncle/son, 1uncle,1uncle/brother, 2 husbands,3 wives from 32 families were investigated. Out of the 140 subjects, (55.7%) were positive for HbsAg and (72.3%) were positive for anti-core. Among the control group (n: 5250), 206 subjects (3.9%) were HbsAg positive. The present survey indicates that there is a significant difference in the prevalence of Hepa¬titis B in the general population and family members of Hepatitis B patients and this is an evidence for horizontal transmission of HBV in household contacts.

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International Journal of Scientific Research in Science and Technology

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Published

2016-12-30

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Volume 2, Issue 6 , November-December-2016

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Research Articles

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[1]
Hamid Omer, Abdel Rahim M. El Hussein, Khalid A Enan, Isam M. Elkhidir, " Intrafamilial Spread of hepatitis B virus in Elfao Province-East of Sudan, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 2, Issue 6 , pp.407-413, November-December-2016.