The Effect of Administered Activity on Patient Radiation dose and Image Quality in SPECT at Korle-Bu Teaching Hospital

Authors

  • Issahaku Shirazu  Medical Radiation Physics Centre, Radiological & Medical Sciences Research Institute, Ghana Atomic Energy Commission, Ghana
  • Theophilus Sackey  National Centre for Radiotherapy and Nuclear Medicine, Department of Nuclear Medicine, Korle-Bu Teaching Hospital, Accra Ghana
  • Ernest Kojo Eduful  National Centre for Radiotherapy and Nuclear Medicine, Department of Nuclear Medicine, Korle-Bu Teaching Hospital, Accra Ghana

DOI:

https://doi.org//10.32628/IJSRST162680

Keywords:

Administered Activity, LEAP, LEHR, Quadrant Bar Phantom, SNR, Flood Field Uniformity Phantom

Abstract

The study discussed two parameters these include; administered activity (patients dose) and image quality. The aim is to determine the relationship between administered activity with resultant patient radiation dose and the quality of images produced. This will help make appropriate recommendation to the technologist and the nuclear medicine physician to produce images that would answer clinical question and at the same time maintain a balance with patient's radiation dose and its prognostic consequences. The study include both quadrant bar phantom study and patient image study in the form of static and dynamic studies. To determine image quality both the quadrant bar phantom and the patients images were assess by using SNR. The quadrant bar phantom was imaged by placing it on flood field uniform phantom which contained the radionuclide. The flood field uniformity phantom was filled with water and then an injected activity, which varied between 5 to 45 mCi of Tc-99 m were added and mixed thoroughly by several shaking for about 5 minutes. Images of the quadrant bar phantom together with real patients’ images with varied injected activities were analyzed. The study shows that as the administered activity increases from 5 to 45mCi the image quality increases significantly, which is based on the increase in SNR. Where the image quality increases from 17.06 to 22.29 in LEAP collimator and 13.56 to 21.51 in LEHR collimator using patients’ static images. In addition, the image quality also increases from 18.26 to 20.44 in LEAP and 13.51 to 21.47 in LEHR collimator using quadrant bar phantom studies. Furthermore, in the of dynamic patients images, the SNR had minimal variation from 5.40 to 29.86 in LEAP and 7.11 to 21.99 in LEHR. Furthermore the reduction in administered activity increases the acquisition time from 7 to 20mins for LEAP collimator and 8 to 22 mins for LEHR collimator. In addition, with the phantom study, the acquisition time increases from 12 to 19 mins for LEAP and 13 to 15 mins for LEHR collimator. Dynamic studies varies slightly in acquisition time just approximately a min increase with increase in administered activity.

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International Journal of Scientific Research in Science and Technology

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Published

2017-02-28

Issue

Volume 3, Issue 1, January-February-2017

Section

Research Articles

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How to Cite

[1]
Issahaku Shirazu, Theophilus Sackey, Ernest Kojo Eduful, " The Effect of Administered Activity on Patient Radiation dose and Image Quality in SPECT at Korle-Bu Teaching Hospital, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 1, pp.204-211 , January-February-2017. Available at doi : https://doi.org/10.32628/IJSRST162680