Synthesis and Antimicrobial Activity of Thiazolidinones Derivatives

Authors

  • N.K. Halikar  Department of Chemistry, Dr. Shantilal Dhanji Devsey College Wada, Palghar, Maharashtra, India
  • G. P. Sadawrte  Department of Chemistry, B.P. S.M.A. Science and K.K.C. Commerce College Chalisgaon, Jalgaon, Maharashtra, India
  • M. J. Gawande  Department of Chemistry, Dr. Shantilal Dhanji Devsey College Wada, Palghar, Maharashtra, India

Keywords:

Benzaldehyde, thioacetic acid, ZnCl2, Antimicrobial Activity.

Abstract

A new synthesis of Schiff base 3a-e was prepared from naphthalene 1 amine. All the naphthalene 1 amine Schiff base were refluxed with thioacetic acid in presence of anhydrous zinc chloride and solvent N,N, dimethyl formamide to form Thiazolidinones 4a-e. All synthesized Thiazolidinones were screening their antimicrobial activity.

References

  1. V.M. Sherekar, S.E. Bhandarkar, Der Pharma Chemica, 2015, 7(3), 1-4.
  2. Vartale SP, Pawde AV, Halikar NK, Kalyankar ND, Pawar YD, RJPBCS 1(4) Page No.? 1061.
  3. J. Matsumoto and S. Minami, J. Med. Chem., 1975,18, 74.
  4. N. Mont, J. Teixid?, J. I. Borrell and C. Oliver Kappe, Tetrahedron Lett., 2003 44, 5385.
  5. V. Oakes and H. N. Rydon, J. Chem. Soc., 1956 10, 4433.
  6. J. Bhatt, B. Shah, H. Shah, P. Trivedi, N. Undavia, N. Desai, Ind. J. Chem., 1994, 33(B), 189-192.
  7. A. Sawale, R. Bendre, P. Patil, RJPBCS, 2012, 3(3), 415-420.
  8. P. Sah, C. Gharu, JCPR, 2012, 9(1), 44-48.
  9. V. Dave, M. Thakor, J. Curr. Chem. Pharm. Sci., 2015, 5(3), 99-104.
  10. K. Swathi, M. Sreenivasulu, N. Pramod, R. Prema, G. Mahaboob Basha, IJBPR, 2014, 5(11), 843-847.
  11. K. Waghmode, J. Chem. Pharm. Res., 2014, 6(5), 1101-1105.
  12. s p. vartale, n d. kalyankar and nk. halikar, Int. J. Chem. Sci.: 11(2), 2013, 1164-1172
  13. R. Yadav, S. Srivastava, S. Srivastava, Ind. J. Chem., 2005, 44(B), 1262-1266
  14. M. Abdullah, Zan. J. App. Sci., 2014, 26(3), 1-12.
  15. N. Seelam, S. Shrivastava, Bull. Korean Chem. Soc., 2011, 32(11), 3996-4000.
  16. S. Ramachandran, P. Shanmugapandiyan, C. Nalini, IJPSR., 2011, 2(6), 1564-1568.
  17. D. Pareek, M. Chaudhary, P. Pareek, K. Ojha, A. Pareek, Int. J. Pharm. Pharm. Sci., 2010, 6(4), 438-455.

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Published

2017-12-31

Issue

Section

Research Articles

How to Cite

[1]
N.K. Halikar, G. P. Sadawrte, M. J. Gawande, " Synthesis and Antimicrobial Activity of Thiazolidinones Derivatives, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 10, pp.06-08, November-December-2017.