Green Chemistry - New Approach in Drug Synthesis

Authors

  • Patil Tejaswini D  
  • Harak Shilpa S.  
  • Dr. Amrutkar Sunil V.  

Keywords:

Green Chemistry, Microwave Assisted Synthesis, Solvent Free Reaction, Sonochemistry

Abstract

Green Chemistry approach is need of the hour in the field of chemistry. Considering the damage to environment, all Pharmaceutical and chemical industry develop interest in new synthetic processes using green chemistry. Most of the drugs are designed, developed and synthesized using various approaches of green chemistry. Microwave assisted synthesis, sonochemistry, solvent free reactions, reuse of catalyst are various approaches of green chemistry used in drug and chemical synthesis. These approaches will be promising in obtaining drug with good yield, less toxic to environment and cost effective.

References

  1. Rajiv Dua,et al, 'Green Chemistry and Environmentally Friendly Technologies: A Review', Middle-East Journal of Scientific Research, 11 (7), 2012, 846-855.
  2. Smita Talaviya and Falguni Majmudar, 'Green chemistry: A tool in Pharmaceutical Chemistry', NHL Journal of Medical Sciences, 1 (1), 2012, 1-13.
  3. Ajay K. Bose, 'A simplified green chemistry approach to the Biginelli reaction using Grindstone Chemistry', Tetrahedron Letters, 45, 2004, 8351?8353.
  4. Santosh V. Padghan et al, 'The Use of Green Chemistry Approach in Organic Synthesis: Focus and Review', www.epitomejournals.com,? I(VII), 2015, 1-9.
  5. Vivek Sharma, 'Applicability of Green Chemistry in Pharmaceutical Processes', Pharma Bio World (Features), 2015, 34-36.
  6. Gopalpur Nagendrappa, 'Organic Synthesis under Solvent-free Condition. An Environmentally Benign Procedure ? I', Resonance, 2002, 59-68.
  7. M. Himaja et al 'Green Technique- solvent free synthesis and its advantages', International journal of research in Ayurveda and Pharmacy, 2(4), 2011, 1079-1086.
  8. Monu Bhardwaj and Neelam, 'The Advantages and Disadvantages of Green Technology', Journal of Basic and Applied Engineering Research, 2(22), 2015, 1957-1960.
  9. Veena Yadav, Nishant Yadav, 'Microwave assisted green chemistry approach to the synthesis of some novel N1-amino-methyl-substituted 1,4-Benzodiazepine derivatives', Archives of Applied Science Research,? 3 (1), 2011, 139-144.
  10. Sonali R. Sharma, 'Green Chemistry, Green Solvents and Alternative Techniques in Organic Synthesis', International Journal of Chemical and Physical Sciences, 4, 2015, 516-520.
  11. W. Wardencki, 'Green Chemistry- Current and Future Issues', Polish Journal of Environmental Studies, 14 (4), 2005, 389-395.
  12. Savita Belwal, 'Green revolution in chemistry by microwave assisted synthesis: A review', Modern Chemistry, 1(3), 2013, 22-25.
  13. Draths CM, Frost JW. 'Microbial catalysis. Synthesis of adipic acid from D-glucose', ACS Symposium Series, 577, Chapter 3, 1994, 32-45.
  14. Anastas PT, Lauren BB, Mary MK, Tracy CW., 'The Role of Catalysis in the design, development, and implementation of Green Chemistry' Catalysis Today,? 55(1), 2000, 11-22
  15. Ingrid M, David S, Marilyn G, Joaudimir C and Johanna F., 'A Greener Approach to Aspirin Synthesis using Microwave Irradiation',? J Chem Edu, 83(4),? 2006,? 628
  16. Steven KM, John G, Chris D, Lisa N, David G, Alica W et al., 'A green-by-design biocatalytic process for atorvastatin intermediate', Green Chem, 12, 2010, 81-86

International Journal of Scientific Research in Science and Technology

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Published

2017-12-31

Issue

Volume 3, Issue 10, November-December-2017

Section

Research Articles

License

Copyright (c) IJSRST

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Patil Tejaswini D, Harak Shilpa S., Dr. Amrutkar Sunil V., " Green Chemistry - New Approach in Drug Synthesis, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 10, pp.63-67, November-December-2017.