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Reservoir and transmission of Visceral Leishmaniasis

Authors(2) :-Dr. Heena Sachdeva, Dr. Manish Sharma

The domestic dog is the most important reservoir of visceral leishmaniasis (VL) in metropolitan areas. The dog develops an intense cutaneous parasitism, favoring infection of sandflies, thereby playing an important role in the epidemiological chain of VL. Importantly, most dogs remain asymptomatic for long periods of time, which contribute to the maintenance and transmission of the disease (Giunchetti, et al., 2006). In Europe, in addition to dogs, rodents are also identified as reservoirs, whereas humans and domestic cats are considered accidental hosts (Poli, et al., 2006). Moreover, leishmanial antibodies were also detected in 33 of 1,220 animals; in 31 of 867 goats (Capra hircus), 1 of 161 cattle (Bos indicus), 1 of 54 wild rats (Rattus sp.), but none of 106 chickens (Gallus domesticus), 26 sheep (Ovis aries), 3 water buffaloes (Bubalus bubalus), and 3 dogs (Canis familiaris). The parasite DNA was detected in 20 of 33 serologically positive blood samples; in 20 goats and 1 cow. This study indicated that goats are also the potential animal reservoirs of human VL in India (Singh, et al., 2013).
Dr. Heena Sachdeva, Dr. Manish Sharma
DNA, VL, Leishmaniasis, Eosophagus, Promastigotes, Phagocytosed, Amastigotes
  1. Giunchetti, R.C., Mayrink, W., Genaro, O., Carneiro, C.M., Correa-Oliveira, R., Martins-Filho, O.A., Marques, M.J., Tafuri, W.L. and Reis, A.B. (2006). Relationship between canine visceral leishmaniasis and the Leishmania (Leishmania) chagasi burden in dermal inflammatory foci. Journal of Comparative Pathology, Vol. 135(2-3): 100-107.
  2. P., Abramo, F., Barsotti, P., Leva, S., Gramiccia, M., Ludovisi, A. and Mancianti, F. (2002). Feline leishmaniasis due to Leishmania infantum in Italy. Veterinary Parasitology, Vol. 106(3): 181- 191.
  3. Singh, N., Mishra, J., Singh, R. and Singh, S. (2013). Animal Reservoirs of Visceral Leishmaniasis in India. J. Parasitology, Vol. 99(1):64-67.
  4. Kamhawi, S. (2006). Phlebotomine sand flies and Leishmania parasites: friends or foes? Trends in Parasitology, Vol. 22(9): 439-445.
  5. Mosser, D.M. and Rosenthal, L.A. (1993). Leishmania macrophage interactions: multiple receptors, multiple ligands and diverse cellular responses. Seminars in Cell Biology, Vol. 4(5):315-322.
  6. Pearson, R.D. and Sousa, A.Q. (1996). Clinical spectrum of leishmaniasis. Clinical Infectious Diseases, Vol. 22(1): 1–13.
  7. Handman, E. and Bullen, D.V.R. (2002). Interaction of Leishmania with the host Macrophage. Trends in Parasitology, Vol. 18(8): 332-334.
  8. Otero, A.C.S, Silva, V.O., Luz, K.G., Palatinik, M., Pirmez, C., Fernandes, O. and Souza, C.P. (2000). Short report: occurrence of Leishmania donovani DNA in donated blood from seroreactive Brazilian blood donors. American Journal of Tropical Medicine and Hygiene, Vol. 62(1): 128-131.
  9. Bosch, R.J., Rodrigo, A.B., Sánchez, P., Galvez, M.V. and Herrera, E. (2002). Presence of Leishmania organisms in specific and non-specific skin lesions in HIV-infected individuals with visceral leishmaniasis. International journal of Dermatology, Vol. 41(10): 670-675.
  10. Symmers, W.S. (1960). Leishmaniasis acquired by contagion a case of marital infection: in Britain. Lancet,Vol.16(7116):127-132.
Publication Details
  Published in : Volume 3 | Issue 1 | January-February 2017
  Date of Publication : 2017-02-28
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 59-60
Manuscript Number : IJSRST173117
Publisher : Technoscience Academy
PRINT ISSN : 2395-6011
ONLINE ISSN : 2395-602X
Cite This Article :
Dr. Heena Sachdeva, Dr. Manish Sharma, "Reservoir and transmission of Visceral Leishmaniasis", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 1, pp.59-60 , January-February-2017
URL : http://ijsrst.com/IJSRST173117