Synthesis, Characterizations and Antimicrobial activity of Oxazolidinone and Imidazolidinone Derivatives

Authors

  • Hitendra N Patel   Department of Chemistry, Shri Jagdishprasad Jhabarmal Tibrewala University Vidhyanagari, Jhunjhunu, Rajashthan, India
  • Dr. B.B.Baldaniya  Department of Chemistry, M. G. Science institute, Navarangpura, Ahmedabad, Gujarat, India

Keywords:

Oxazolinone, Imidazol-5-Ones, Antibacterial Activity, Antifungal Activity.

Abstract

Glycine (1) was allowed to react with substituted benzoyl chloride (2) to give substituted hippuric acid(3). Different aldehydes were treated with compound(3a-b)to get 1,3-oxazole-5-ones derivative(4a-j, 7a-j). These oxazolinones were treated with various aromatic amines to get various imidazol-5-ones derivatives (5a-j, 6a-j, 8a-j, 9a-j). Compounds characterized by elemental analyses like IR spectra, NMR spectra and GCMS. The products have been tested for their antifungal and antibacterial activity against gram (+) ve and gram (-) ve bacteria.

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International Journal of Scientific Research in Science and Technology

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Published

2017-04-30

Issue

Volume 3, Issue 3, March-April-2017

Section

Research Articles

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How to Cite

[1]
Hitendra N Patel , Dr. B.B.Baldaniya, " Synthesis, Characterizations and Antimicrobial activity of Oxazolidinone and Imidazolidinone Derivatives, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 3, pp.211-216 , March-April-2017.