Synthesis, Characterizations and Antimicrobial activity of Oxazolidinone and Imidazolidinone Derivatives

Authors(2) :-Hitendra N Patel , Dr. B.B.Baldaniya

Glycine (1) was allowed to react with substituted benzoyl chloride (2) to give substituted hippuric acid(3). Different aldehydes were treated with compound(3a-b)to get 1,3-oxazole-5-ones derivative(4a-j, 7a-j). These oxazolinones were treated with various aromatic amines to get various imidazol-5-ones derivatives (5a-j, 6a-j, 8a-j, 9a-j). Compounds characterized by elemental analyses like IR spectra, NMR spectra and GCMS. The products have been tested for their antifungal and antibacterial activity against gram (+) ve and gram (-) ve bacteria.

Authors and Affiliations

Hitendra N Patel
Department of Chemistry, Shri Jagdishprasad Jhabarmal Tibrewala University Vidhyanagari, Jhunjhunu, Rajashthan, India
Dr. B.B.Baldaniya
Department of Chemistry, M. G. Science institute, Navarangpura, Ahmedabad, Gujarat, India

Oxazolinone, Imidazol-5-Ones, Antibacterial Activity, Antifungal Activity.

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Publication Details

Published in : Volume 3 | Issue 3 | March-April 2017
Date of Publication : 2017-04-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 211-216
Manuscript Number : IJSRST173340
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Hitendra N Patel , Dr. B.B.Baldaniya, " Synthesis, Characterizations and Antimicrobial activity of Oxazolidinone and Imidazolidinone Derivatives", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 3, pp.211-216 , March-April-2017.
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