Biotechnological Aspects of Production, Characterization and Application of Keratinase

Authors(4) :-Sadia Azaz, Sikander Ali, Afaq Ahmed, Maryam Javid

Keratin is insoluble biopolymer and mainly present in tissues of birds, amphibians, reptiles and mammals. Many industries use keratin as raw material and accumulation of keratin causes many environmental problems. To reduce keratin accumulation there should be a need to develop an easy and cheap process for environmental remediation of keratin. Microbial keratinase, a proteolytic enzyme, is used to reduce pollution and is mainly obtained from Keratinophilic fungi, bacteria and actinomyces and Streptomyces. Keratin is degraded in prokaryotes by degrading serine protease and in eukaryotes by ubiquitin (Ub)-proteasome pathway (UPP). Keratinase used to degrade feathers of poultry and converted into high energy input feather meal, in leather industry for management of wastes which mainly causes the water pollution, by producing bio hydrogen from solid wastes. In this review it is investigated that microbial keratinase is less expensive than conventional production of keratinase and have many advantages to reduce pollution.

Authors and Affiliations

Sadia Azaz
Institute of Industrial Biotechnology (IIB) Govt. College University Lahore, Pakistan
Sikander Ali
Institute of Industrial Biotechnology (IIB) Govt. College University Lahore, Pakistan
Afaq Ahmed
Institute of Industrial Biotechnology (IIB) Govt. College University Lahore, Pakistan
Maryam Javid
Institute of Industrial Biotechnology (IIB) Govt. College University Lahore, Pakistan

Keratinophilic fungi, Streptomyces, actinomyces, serine protease, ubiquitin proteasome pathway, bio-hydrogen.

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Publication Details

Published in : Volume 3 | Issue 4 | May-June 2017
Date of Publication : 2017-06-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 327-336
Manuscript Number : IJSRST173467
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Sadia Azaz, Sikander Ali, Afaq Ahmed, Maryam Javid, " Biotechnological Aspects of Production, Characterization and Application of Keratinase", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 4, pp.327-336, May-June-2017.
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