Hypoxanthine-Guanine Phosphoribosy ltransferase (HPRT) Deficiency : Lesch-Nyhan Syndrome

Authors

  • Sikander Ali  Institute of Industrial Biotechnology (IIB), GC University Lahore, Pakistan
  • Jalisha Sagir  Institute of Industrial Biotechnology (IIB), GC University Lahore, Pakistan
  • Maha Khan  Institute of Industrial Biotechnology (IIB), GC University Lahore, Pakistan

Keywords:

Lesch-Nyhan, HGPRT, Hyperuricemia

Abstract

Lesch-Nyhan is a genetic metabolic disease. It involves disorder related to uric acid in which attitude problems are dominant. The changed and wild genes will tell us about this disorder that it is a disorder of X-chromosome. This disease is dominant in men. It involves completely impaired action of HGPRT. In this disease excess quantity of uric acid produced in joints of the body and other parts. It also causes dis functioning of gout. It also causes problems in brain function. It also involves physical disability. The victim of this disease demands for extra care. Different clinical methods and techniques can be used to improve the attitude of the victims suffering from this disease.

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International Journal of Scientific Research in Science and Technology

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Published

2017-06-23

Issue

Volume 3, Issue 4, May-June-2017

Section

Research Articles

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How to Cite

[1]
Sikander Ali, Jalisha Sagir, Maha Khan, " Hypoxanthine-Guanine Phosphoribosy ltransferase (HPRT) Deficiency : Lesch-Nyhan Syndrome, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 4, pp.490-498, May-June-2017.