Electrospun Polycaprolactone Nanofibers for Sustained Release of Naringin

Authors

  • R. Ranjith  Department of Advanced Zoology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India
  • S. Balraj  Department of Advanced Zoology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India
  • J. Ganesh  Department of Advanced Zoology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India
  • M. C. John Milton  

Keywords:

Electrospinning, Polycaprolactone Nanofibers, Naringin, Drug Delivery

Abstract

Electrospun nanofibers have enormous potential to deliver bioactive molecules in a sustained manner for various drug delivery applications. In this study, naringin loaded polycaprolactone nanofibers were fabricated using electrospinning technique. The scanning electron microscopy results showed an increased fiber diameter in naringin loaded polycaprolactone nanofibers compared with control. Further, an X-ray diffraction analysis showed amorphization of naringin in nanofibers during the encapsulation process. Furthermore, sustained release of naringin was observed for 12 days. These results suggested that naringin loaded polycaprolactone nanofibers helps to deliver encapsulated naringin in sustained manner and also it can be advantageous in various drug delivery and tissue engineering applications.

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International Journal of Scientific Research in Science and Technology

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Published

2017-08-31

Issue

Volume 3, Issue 6, July-August-2017

Section

Research Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
R. Ranjith, S. Balraj, J. Ganesh, M. C. John Milton, " Electrospun Polycaprolactone Nanofibers for Sustained Release of Naringin, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 6, pp.235-238, July-August-2017.