Electrospun Polycaprolactone Nanofibers for Sustained Release of Naringin

Authors(4) :-R. Ranjith, S. Balraj, J. Ganesh, M. C. John Milton

Electrospun nanofibers have enormous potential to deliver bioactive molecules in a sustained manner for various drug delivery applications. In this study, naringin loaded polycaprolactone nanofibers were fabricated using electrospinning technique. The scanning electron microscopy results showed an increased fiber diameter in naringin loaded polycaprolactone nanofibers compared with control. Further, an X-ray diffraction analysis showed amorphization of naringin in nanofibers during the encapsulation process. Furthermore, sustained release of naringin was observed for 12 days. These results suggested that naringin loaded polycaprolactone nanofibers helps to deliver encapsulated naringin in sustained manner and also it can be advantageous in various drug delivery and tissue engineering applications.

Authors and Affiliations

R. Ranjith
Department of Advanced Zoology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India
S. Balraj
Department of Advanced Zoology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India
J. Ganesh
Department of Advanced Zoology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India
M. C. John Milton

Electrospinning, Polycaprolactone Nanofibers, Naringin, Drug Delivery

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Publication Details

Published in : Volume 3 | Issue 6 | July-August 2017
Date of Publication : 2017-08-31
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 235-238
Manuscript Number : IJSRST173648
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

R. Ranjith, S. Balraj, J. Ganesh, M. C. John Milton, " Electrospun Polycaprolactone Nanofibers for Sustained Release of Naringin, International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 6, pp.235-238, July-August-2017. Available at doi : 10.32628/IJSRST173648
Journal URL : http://ijsrst.com/IJSRST173648

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