Ultrasound Assisted Convenient and Efficient Protocol for Synthesis of Dihydropyrimidine-2-thiones

Authors(5) :-Ashok S. Pise, Arvind S. Burungale, Ramesh B. Gawade, Santosh S. Devkate, Sunil D. Jadhav

Chalones were prepared by condensation of various substituted aromatic aldehydes or heterocyclic aldehydes and acetophenone in alkaline ethanol, while pyrimidine-2-thione derivatives were prepared by condensation of chalcones and thiourea under ultrasonic irradiation at room temperature. The most important advantage of ultrasound irradiation was observed and high yields of products were obtained after 10-15 min. sonication.

Authors and Affiliations

Ashok S. Pise
Department of Chemistry, Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, India
Arvind S. Burungale
Department of Chemistry, S. M. Joshi College Hadapsar, Pune, Maharashtra, India
Ramesh B. Gawade
Department of Chemistry, S. M. Joshi College Hadapsar, Pune, Maharashtra, India
Santosh S. Devkate
Department of Chemistry, S. M. Joshi College Hadapsar, Pune, Maharashtra, India
Sunil D. Jadhav
Department of Chemistry, Mahatma Phule Mahavidyalaya, Panvel, Raigad, Maharashtra, India

Chalcones, Dihydropyrimidine-2-thione, Cu(I) catalyst, Sodamide, Ultrasound irradiation.

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Publication Details

Published in : Volume 3 | Issue 8 | November-December 2017
Date of Publication : 2017-12-31
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 1073-1075
Manuscript Number : IJSRST1738238
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Ashok S. Pise, Arvind S. Burungale, Ramesh B. Gawade, Santosh S. Devkate, Sunil D. Jadhav, " Ultrasound Assisted Convenient and Efficient Protocol for Synthesis of Dihydropyrimidine-2-thiones", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 8, pp.1073-1075, November-December-2017.
Journal URL : http://ijsrst.com/IJSRST1738238

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