Phenotype Frequencies of Blood Group Systems (ABO, Rh, Kell) Among Deferent Patients in Jaipur-India

Abstract

Background: With the industrial revolution of modern equipment and preparation of reagents, but in most blood banks; blood transfusions are done based on ABO & Rh antigens for pre-transfusion compatibility testing and achieved by random cross-matching of available units in the inventory storage. Unknown phenotype blood group for clinically significant antigens may cause in immunization Aim: To determine the frequency of ABO, kell, Rh blood grouping, Du testing and antigen profile. Materials and Methods: A total of 103 samples were collected from deferent patients at Nims and SDM Hospital in Jaipur-India. Laboratory investigations were have done to all the studied patients including: ABO, Rh blood grouping and Du testing have done by (BioVue cassettes based on Column Agglutination Technology), finally antigen profile (Rh- Kell Phenotype) by DiaMed ID-Card (C-c-E-e-K-Ctl, Monoclonal). Results: Total of 103 patients of deferent diseases 54 (52.5%) were males and 49 (47.5%) were females. The prevalence of Rh positive was 82.5%.The most common in distribution of ABO group system was B group (40.5%) flowed by O (26.5%) then A group (23%). The most antigen frequent was antigen (e: 87.4%) and flowed by D: 82.5%, C: 70.8%, c: 65%, E: 11.6%, while kell antigen was (2.9%). Conclusion: Our study, first step to make a rare donor antigens database bank and patients’ antibodies also, to provide compatible blood to all multiple blood transfused, alloimmunized patients and enhance safety in transfusion medicine.