One Pot Synthesis of 6,7-Diimino imidazolo[2,3-b]pyrimido[5,6-e] pyrimido[2,3-b][1,3]benzothiazole Derivatives

Authors

  • Sambhaji P. Vartale  P.G. Research Centre, Department of Chemistry, Yeshwant Mahavidyalaya, Nanded, Maharashtra, India
  • Sandeep G. Sontakke   Department of Chemistry, Dr. B. N. Purandare Arts, Smt.S.G.Gupta Commerce and Science College, Lonavala , Maharashtra, India
  • Prashant N. Ubale  P.G. Research Centre, Department of Chemistry, Yeshwant Mahavidyalaya, Nanded, Maharashtra, India

Keywords:

Benzothiazole, Pyrimido, DMF, Potassium Carbonate, Spectral Properties.

Abstract

We have reported the synthesis of 6,7-Diimino imidazolo[2,3-b]pyrimido[5,6-e]pyrimido[2,3-b][1,3]benzothiazole derivatives by condensing 3-Cyano-4-imino-2-methylthio-4H-pyrimido[1,2-a]benzimidazole with 2-Amino benzothiazole derivatives in presence of N,N’-dimethyl formamide and anhydrous potassium carbonate as a catalyst under reflux condition. The structures of all newly synthesized cyclic compounds were confirmed on the basis of spectral analysis, IR, 1H NMR and Mass spectral properties.

References

  1. P.Venkatesh and S.N.Pandeya, Int.J. ChemTech Res., 2009, 1(4), 1354-1358.
  2. F Russo, G Romeo, N Santagati, A Caruso, V Cutuli, D Amore, European Journal of Medicinal Chemistry, 1994, 29, 7-8; 569-578.
  3. Shivani Choudhary, Suvarna G. Kini and Muhammad Mubeen, Der Pharma Chemica, 2013, 5(4), 213-222.
  4. Mariappan G, Prabhat P, Sutharson L, Banerjee J, Patangia U, Nath S, Journal of the Korean Chemical Society, 2012, 56(2), 251-256.
  5. Mariappan G, Prabhat P, Sutharson L, Patangia U, Nath S, Banerjee J, European Journal of Medicinal Chemistry, 2010, 45(7), 2938-2942.
  6. Priya P. Netalkar, Sandeep P. Netalkar, Srinivasa Budagumpi, Vidyanand K. Revankar, European Journal of Medicinal Chemistry, 2014, 79, 47-56.
  7. Kochichiro Y, Katsumi G, Kazuya Y, Tominori M, and Goro T, Journal of Medicinal Chemistry, 1990, 33(8), 2192-2196.
  8. Tashfeen Akhtar, Shahid Hameed, Najim Al-Masoudi, Roberta Loddo, Paolo Colla,? Acta Pharmaceutica, 2008, 58(2), 135-149.
  9. Yaseen A. Al-Soud, Haitham H. Al-Sa’doni, Bahjat Saeed, Ihsan H. Jaber, Mohammad O. Beni-Khalid, Najim A. Al-Masoudi, Tahsin Abdul-Kadir, Paolo La Colla, Bernardetta Busonera, Tiziana Sanna and Roberta Loddo, ARKIVOC, 2008, (xv), 225-238.
  10. Suvarna Kini, S.P. Swain and A.M. Gandhi, Indian Journal of Pharmaceutical Sciences, 2007, 69(1), 46-50.

Downloads

Published

2017-12-15

Issue

Section

Research Articles

How to Cite

[1]
Sambhaji P. Vartale, Sandeep G. Sontakke , Prashant N. Ubale, " One Pot Synthesis of 6,7-Diimino imidazolo[2,3-b]pyrimido[5,6-e] pyrimido[2,3-b][1,3]benzothiazole Derivatives, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 9, pp.59-61, November-December-2017.