Synthesis and Antimicrobial Screening of Metal Complexes of 1-(5-Chloro-2-Hydroxyphenyl)-3-(2,4-Dichlorophenyl) Propane-1,3-Dione

Authors(4) :-D. D. Suryawanshi, A. D. Suryawanshi, A. S. Padampalle, A. S. Rajbhoj

1-(5-Chloro-2-Hydroxyphenyl)-3-(2,4-Dichlorophenyl) Propane-1,3-Dione and its metal complexes have been synthesized by conventional method. The diketone is offered by employing Baker- Venkatraman rearrangement. The synthesized compounds were confirmed by the spectroscopic analysis such as UV, IR , 1H-NMR, 13C-NMR, mass, elemental analysis, magnetic susceptibility, XRD and evaluated for antibacterial screening.

Authors and Affiliations

D. D. Suryawanshi
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India
A. D. Suryawanshi
Department of Physics, B. J. College Ale.,Pune, Maharashtra, India
A. S. Padampalle
Department of Physics, S. C. S. College Omerga.,Osmanabad, India
A. S. Rajbhoj
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India

Baker-Venkatraman rearrangement, metal complexes, XRD, thermal study.

  1. M. Thiyagarajan, S.S. Sharma, Life Sci., 74, (2004), 969.
  2. T. Dziemboska, Z. Rozwadowski, Curr. Org. Chem, 5, (2001), 289.
  3. S. Antony, R. Kuttan, G. Kuttan, Immun. Invest, (1999), 28, 291.
  4. V. Fargeas, M. Baglouch, E. Muley, J. Baffreau, D. Mehard, P. Gosselin, J. P. Berge, C. Barthomeuf, Tetrahedron, 60, (2004), 1035
  5. J. Christoffers, H. Oertling, P. Fisher, W. Frey, Tetrahedron, 59, (2003), 3769
  6. A. R. Katritzki, Z. Wang, M. Wang, C. R. Wilkinson, D. Hall, N. G. Akhmedor, J. Org. Chem, 69, (2004), 6617
  7. D. Pokormy, W. Striner, D. W. Ribbons, Biotechnol, 15, (1997), 291
  8. G. Grogan, J. Mol. Catal. B. Enzyme, 19, (2002), 73
  9. A. Siedle in comprehensive Coordination Chem., 1987, Wilkinson, pergamon press, Oxford, vol. 2 cha 15,4 pp365.
  10. T. Nishiyama, S. Shiotsu, T Polym. Degrad & Stab, 2002, 76, 435-439.
  11. S. T. Heller, S. R. Natrajan, Org. Lett. 2006, 8, 2675.
  12. D. Simoni, F. Invidita, R. Rondanin, S. Grimaudo, G. Cannizzo, E. Barbusca, F. Porretto, N. Alessandro and M. Tolomeo, J Med Chem., 1999, 42, 4961.
  13. V. V. Alekseev, K. N. Zelenin and S. I. Yakimovich, Russ J Org Chem., PO1995, 31, 868.
  14. R Kumar and C. Y. Joshi, Arkivoc, 2007, 9, 142.
  15. O Kuzueva, Y Burgart, V Saloutin and O Chupakhin, Chemistry of Heterocyclic compounds, 2001, 37, 1130.
  16. N Acton, A Brossi, D L Newton and M B Sporn, J Med Chem., 1980, 23, 805-809.
  17. G Crouse, M McGowan and R Boisvenue, J Med Chem., 1989, 32, 2148.??????????????????????????? ?????????????????????????????????????????????????I Bennett, NJ Broom, R Cassels, J S Elder, N D Masson and O’ Hanlon P L, Nioorg Med Chem Lett., 1999, 9, 1847-1852.Chate A. V. Bhagat S. S. and Gill C. H., J. Heterocyclic Chem, 2011, DOII. 1002/955.I Andrae, A Bringhen, F Bohm, H Gonzenbach, T Hill, Mulroy L and T G Truscott, J Photochem Photobiol B: Biol., 1997, 37, 147-150.A. V. Chate , R. Joshi, P. Mandhane, C. H. Gill, J. Korean Chemikcal Soci. 2011, 55, 4.
  18. A. V. Chate, R. S. Joshi, V. Badadhe and C. H. Gill, Bull. Korean Chem. Soc, 2011, vol.32, no. 11, 3887.
  19. Carvajal J. R, Roisnel T, Winplotr, A graphic tool for powder diffraction, Laboratoire Leon Brillouin (ceal/cnrs) 91191 Gif sur Yvette Cedex, France, 2004.
  20. Shoemaker D. P., Garland C.W., Experiments in Physical Chemistry, 5th ed., McGraw-Hill International Edition, New York, 1989.
  21. Deshmukh M. B, S. Dhongade-Desai, Chavan S. S, Indian J. Chem. 44 (2005) 1659.
  22. J. Sestak, V. Satava, W. W. Wendland, Therm. Chem. Acta, 7, (1973), 333.
  23. J. T. Makodi, A. S. Aswar, J. Indian Chem Soc, 80 (1), 2003,44.
  24. Sharma O, Singla R, Shrivastava B, Bhat V, Shenoy G, Sreenivasan K, Indo Globl J. of Pharmaceutical Sciences; 2012; 2(1), 70-75.

Publication Details

Published in : Volume 3 | Issue 9 | November-December 2017
Date of Publication : 2017-12-15
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 75-78
Manuscript Number : IJSRST173915
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

D. D. Suryawanshi, A. D. Suryawanshi, A. S. Padampalle, A. S. Rajbhoj, " Synthesis and Antimicrobial Screening of Metal Complexes of 1-(5-Chloro-2-Hydroxyphenyl)-3-(2,4-Dichlorophenyl) Propane-1,3-Dione", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 9, pp.75-78, November-December-2017.
Journal URL : http://ijsrst.com/IJSRST173915

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