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Pectin - Ethanolamine Graft Copolymer Hydrogel for Ointment and Transdermal Patches Consist of Tridax Procumbens L. Ethanol-Water Extract as Antiseptic and Antifungal Agent
Authors(1) :-Prashant B. Sutar
Currently research has been carried out for the development of transdermal drug delivery systems. Specific transdermal drug delivery system is chemically modified pectin based hydrogels. This modified gel is used to carry ethanol-water extract of Tridax procumbens L. as antiseptic, antifungal. Pectin forms gel with crosslinking agents like divalent or multivalent cations, glutaraldehyde etc. Transdermal patches and ointment with petroleum wax made from the cross-liked modified pectin gel and the leaf extract of plant in ethanol-water were loaded through diffusion method. In the current study an attempt has been made to improve the properties of the pectin gels by graft copolymerization with ethanolamine and the swelling properties were modified by varying concentration of crosslinking agent, glutaraldehyde and used for various biomedical applications,. Antiseptic and antifungal activity of loaded hydrogel were studied.
Hydrogel, pectin modification, Tridax procumbens L. Transdermal patches, ointment.
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Published in : Volume 3 | Issue 9 | November-December 2017
Date of Publication : 2017-12-15
License: This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 222-229
Manuscript Number : IJSRST173944
Publisher : Technoscience Academy
PRINT ISSN : 2395-6011
ONLINE ISSN : 2395-602X
Cite This Article :
Prashant B. Sutar, "Pectin - Ethanolamine Graft Copolymer Hydrogel for Ointment and Transdermal Patches Consist of Tridax Procumbens L. Ethanol-Water Extract as Antiseptic and Antifungal Agent", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 9, pp.222-229, November-December-2017
URL : http://ijsrst.com/IJSRST173944