Home > Archives > IJSRST173947 IJSRST-Library

Synthesis & Characterization of Pectin - N-isopropyl acrylamide modified graft co-polymers for potential Applications

Authors(1) :-Prashant B. Sutar

Recently research is being carried out for the development of various copolymers, modified polymers for various potential applications like coatings, composite, paints, adhesives, drug delivery systems, hydrogel-based delivery devices can be used for oral, rectal, ocular, epidermal and subcutaneous application. tablet coatings, etc.[1] In this work we tried to improve the properties of the polysaccharide based polymers pectin, by graft copolymerization with N-isopropylacrylamide polymers using emulsion polymerization technique. The effect of various variables like initiator concentration, monomer concentration, temperature and time has been studied. The grafted copolymer was characterized by Fourier transform infrared spectroscopy (FT-IR), organic elemental analysis, differential scanning calorimetry (DSC) and X-ray diffraction (XRD). FT-IR studies indicated incorporation of amide group. Rheological behavior of pectin solution was compared with that of the grafted copolymer. The comparative rheological properties of pectin and grafted copolymer indicated change in the property of the product. Differential scanning calorimetry and XRD suggested formation of the grafted copolymer.
Prashant B. Sutar
Graft copolymerization,; Pectin; N-isopropyl acrylamide; Rheology, differential scanning calorimetry .
  1. Prashant B. Sutar. , Rakesh K. Mishra, Kunal Pal, Ajit K. Banthia 'Development of pH sensitive polyacrylamide grafted pectin hydrogel for controlled drug delivery system’, J Mater Sci: Mater Med, DOI 10. 1007/s10856-007-3162-y.
  2. R. K. MISHRA1, J. P. SINGHAL1, M. DATT1, A. K. BANTHIA2Amidated pectin: synthesis,characterization and cytocompatibility study, Journal of Applied Biomaterials & Biomechanics 2007; Vol. 5 no. 2: 00-00
  3. J. John Meister, Polymer Modification (principle, techniques and application), {Publisher} Ed. 2000, page number-331.
  4. G. F. Fanta, (1973). In R. J. Ceresa (Ed. ), (Vol. 1) (pp. 11 Synthesis of graft and block copolymers of starch, block and graft copolymerisation, New york: Wiley.
  5. N. A. Peppas, A. G. Mikos, Preparation methods and structure of hydrogels, in: N. A. Peppas (Ed. ), Hydrogels in Medicine and Pharmacy, Vol. 1, CRC Press, Boca Raton, FL, 1986, pp. 1?27.
  6. Walter, R. H. (1991) The Chemistry and Technology of Pectin, Academic Press, New York, NY, USA
  7. Hawang, J. and Kokini, J. L. (1992) Carbohydr. Polym. 19, 41-52
  8. M. B. Huglin and M. B. Zakaria , Swelling properties of copolymeric hydrogels prepared by gamma irradiation. Journal of Applied Polymer Science31 (1986), pp. 457-475.
  9. Anuradha Mishra , Malvika Bajpai, Synthesis and characterization of polyacrylamide grafted copolymer of Kundoor mucilage, J. Applied polymer science 98:1186-1191,2005,vol-98 issue-3.
  10. Y. Kimura, in: T. Tsuruta, et al. (Ed. ), Biomedical Applications of Polymeric Materials, CRC Press, Boca Raton, FL,1993, pp. 8 -9.
  11. Yalpani M. Polysaccharides: synthesis, modifications and structure/property relations. New York: Elsevier Science
  12. Publishers, 1988. p. 34-5.
  13. BeMiller JM. An introduction to pectins: structure and properties. In: Fishman ML, Jen JJ, editors. Chemistry and function of pectins. Washington, DC: American Chemical Society, 1986. ACS Series 310, p. 2-13.
  14. Rombouts FM, Thibault JF, Mercier C. Oxidative enzymecatalyzed cross-linkingof beet pectins. US Patent No. 4,672,034, 1987.
  15. Hamidreza,G. ; Kope kov?,P. ; P-Y Yeh and J Kope ek, Biodegradable and pH- sensitive hydrogels: synthesis by a polymer-polymer reaction,. Macromol. Chem. Phys. 1996;197: 965-980.
  16. A. T. Metters, K. S. Anseth, and C. N. Bowman. Fundamental Studies of a Novel, Biodegradable PEG-b-PLA Hydrogel,Polymer, 2000; 41, 3993-4004
  17. Marra, S. P. ; Ramesh, K. T. ; DouglasA. S. “Mechanical characterization of. Active polymer gels” Proc. SPIE 2000;3987: 166
  18. Polymer Modification (principle, techniques and application, John J. Meister. Edition 2000, page number-331.
  19. Targegeted & Controlled Drug Delivery Novel Carrier Systems, S. P. Vyas , R . P. Khar1st edition 2002,page1-5.
  20. Shah,S. B. ;Patel,C. P. ;Trivedi,H. C. Cericinducedgrafting ofacry- lonitrile on to sodium alginate: Kinetics and mechanism and effect ofreaction medium. HighPerformancePolymers,1993,6,193-200.
  21. Shah,S. B. ;Patel,C. P. ;Trivedi,H. C. Fenton’s reagent-initiatedgraft copolymerizationofacrylonitrile onsodiumalginate. J. Appl. Polym. Sci. 1994a,51,1421-1426.
  22. Shah, S. B. ;Patel, C. P. ; Trivedi, H. C. Kinetics and reaction mechanismoffenton’sreagent-initiatedgraftcopolymerizationofacryloni- trileonsodiumalginate. J. Appl. Polym. Sci. 1994b,52,857-860.
  23. Mishra, A.; Bajpai, M. Graft copolymerizationofpolyacrylamide on totamarindmucilage. J. Macromol. Sci. PureAppl. Chem. 2006, 43A,315?326.
  24. Mishra, A. ;Srinivasan, R. ;Gupta,R. Psyllium-g-polyacrylamide: Synthesisandcharacterization. Polym. Bull. 2002,48,439?444.
  25. Tripathy, T. Synthesisofpolyacrylamide graftedcarboxymethyl cellu- loseandevaluationofitsflocculationcharacteristics. J. Polym. Mater. 2007,56,461?482.
  26. Gomez-D??az, D.; Navaza, J. M. Rheology of aqueous solutions of foodadditives:Effectofconcentration,temperatureandblending. J. Food Eng. 2003,56,387?392.
  27. Krishnamoorthi, S. ; Mal,D. ;Singh,R. P. Characterizationofgraft copolymer basedonpolyacrylamide and dextran. Carbohyd. Polym. ????????? 2006,69,371?377.
Publication Details
  Published in : Volume 3 | Issue 9 | November-December 2017
  Date of Publication : 2017-12-15
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 237-245
Manuscript Number : IJSRST173947
Publisher : Technoscience Academy
PRINT ISSN : 2395-6011
ONLINE ISSN : 2395-602X
Cite This Article :
Prashant B. Sutar, "Synthesis & Characterization of Pectin - N-isopropyl acrylamide modified graft co-polymers for potential Applications", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 9, pp.237-245, November-December-2017.
Journal URL : http://ijsrst.com/IJSRST173947

Article Preview