Clean and green synthesis of structurally diverse 4H-benzo[b]pyrans derivatives in water

Authors(2) :-Somnath S. Gholap, Vinod R. Kadu and Sachin S. Lokhande

Magnesium sulphate has been reported as a cheap and readily available common desk reagent for the synthesis of highly functionalized 4H-benzo[b]pyran derivatives. The synthesis of target compounds was accomplished by one pot multicomponent reaction of aldehydes, malononitrile and dimedone or 4-hydroxycoumarin, aldehyde in under reflux temperature. The corresponding 4H-benzo[b]pyrane derivatives were obtained in good excellent yield under optimized reaction conditions. The methodology prescribed here was found to be adventitious over reported protocols in terms of generality, environment friendliness and economic viability.

Authors and Affiliations

Somnath S. Gholap
Post graduate Department and Research Centre, Padmashri Vikhe Patil College, Pravaranagar (Loni Kd.),Rahata, Ahmednagar, (MS), India
Vinod R. Kadu and Sachin S. Lokhande
Post graduate Department and Research Centre, Padmashri Vikhe Patil College, Pravaranagar (Loni Kd.),Rahata, Ahmednagar, (MS), India

Magnesium sulphate, 4H-Benzo[b]pyran, Dimedone, Aldehyde, Malononitrile, Water medium

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Publication Details

Published in : Volume 3 | Issue 9 | November-December 2017
Date of Publication : 2017-12-15
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 278-282
Manuscript Number : IJSRST173955
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Somnath S. Gholap, Vinod R. Kadu and Sachin S. Lokhande, " Clean and green synthesis of structurally diverse 4H-benzo[b]pyrans derivatives in water", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 9, pp.278-282, November-December-2017.
Journal URL : http://ijsrst.com/IJSRST173955

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