Clean and green synthesis of structurally diverse 4H-benzo[b]pyrans derivatives in water

Authors

  • Somnath S. Gholap  Post graduate Department and Research Centre, Padmashri Vikhe Patil College, Pravaranagar (Loni Kd.),Rahata, Ahmednagar, (MS), India
  • Vinod R. Kadu and Sachin S. Lokhande  Post graduate Department and Research Centre, Padmashri Vikhe Patil College, Pravaranagar (Loni Kd.),Rahata, Ahmednagar, (MS), India

Keywords:

Magnesium sulphate, 4H-Benzo[b]pyran, Dimedone, Aldehyde, Malononitrile, Water medium

Abstract

Magnesium sulphate has been reported as a cheap and readily available common desk reagent for the synthesis of highly functionalized 4H-benzo[b]pyran derivatives. The synthesis of target compounds was accomplished by one pot multicomponent reaction of aldehydes, malononitrile and dimedone or 4-hydroxycoumarin, aldehyde in under reflux temperature. The corresponding 4H-benzo[b]pyrane derivatives were obtained in good excellent yield under optimized reaction conditions. The methodology prescribed here was found to be adventitious over reported protocols in terms of generality, environment friendliness and economic viability.

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International Journal of Scientific Research in Science and Technology

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Published

2017-12-15

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Volume 3, Issue 9, November-December-2017

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Research Articles

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How to Cite

[1]
Somnath S. Gholap, Vinod R. Kadu and Sachin S. Lokhande, " Clean and green synthesis of structurally diverse 4H-benzo[b]pyrans derivatives in water, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 9, pp.278-282, November-December-2017.