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Clean and green synthesis of structurally diverse 4H-benzo[b]pyrans derivatives in water

Authors(2) :-Somnath S. Gholap, Vinod R. Kadu and Sachin S. Lokhande

Magnesium sulphate has been reported as a cheap and readily available common desk reagent for the synthesis of highly functionalized 4H-benzo[b]pyran derivatives. The synthesis of target compounds was accomplished by one pot multicomponent reaction of aldehydes, malononitrile and dimedone or 4-hydroxycoumarin, aldehyde in under reflux temperature. The corresponding 4H-benzo[b]pyrane derivatives were obtained in good excellent yield under optimized reaction conditions. The methodology prescribed here was found to be adventitious over reported protocols in terms of generality, environment friendliness and economic viability.
Somnath S. Gholap, Vinod R. Kadu and Sachin S. Lokhande
Magnesium sulphate, 4H-Benzo[b]pyran, Dimedone, Aldehyde, Malononitrile, Water medium
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Publication Details
  Published in : Volume 3 | Issue 9 | November-December 2017
  Date of Publication : 2017-12-15
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 278-282
Manuscript Number : IJSRST173955
Publisher : Technoscience Academy
PRINT ISSN : 2395-6011
ONLINE ISSN : 2395-602X
Cite This Article :
Somnath S. Gholap, Vinod R. Kadu and Sachin S. Lokhande, "Clean and green synthesis of structurally diverse 4H-benzo[b]pyrans derivatives in water", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 3, Issue 9, pp.278-282, November-December-2017
URL : http://ijsrst.com/IJSRST173955