Genetic Analysis, Health Issues and Consanguineous Marriage in Muslim Community

Authors

  • Mohd Younis  Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, Tamil Nadu, India
  • K. Sasikala  Human Genetics Laboratory, Department of Zoology, Bharathiar University, Coimbatore, Tamil Nadu, India
  • A. Vijaya Anand  Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, Tamil Nadu, India
  • Javaid Iqbal  Department of Zoology, Barkatullah University, Bhopal, Madhya Pradesh, India
  • Som Kailash  Department of Zoology, Barkatullah University, Bhopal, Madhya Pradesh, India
  • Meraj Ud Din Hura  Department of Zoology, Barkatullah University, Bhopal, Madhya Pradesh, India

Keywords:

Muslim Community, Consanguineous Marriages, Genetic Syndromes, Rare Genetic Disorders.

Abstract

Consanguineous marriage is the union of individuals have common ancestors. The rate of consanguinity is high among the Muslim community around the world, especially in Arab countries. Many rare genetic disorders and new genetic syndromes, congenital malformations, morbidity, mortality and reproductive wastage have been observed to increase frequency in the consanguineous marriage. Some other abnormalities include low birth weight, cleft lips, congenital heart defect, neurological defect (hypertension, schizophrenia, Alzheimer disease and bipolar disorder), progressive pseudo rheumatoid dysplasia and cancer are observed among the offspring of consanguineous marriages. Progressive rheumatoid dysplasia a rare autosomal recessive disorder is also found among the offspring of consanguineous marriage couples. The frequency of consanguineous marriage is high in uneducated, low educated group and mostly in rural population.

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International Journal of Scientific Research in Science and Technology

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2018-02-28

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Volume 4, Issue 2, January-February-2018

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[1]
Mohd Younis, K. Sasikala, A. Vijaya Anand, Javaid Iqbal, Som Kailash, Meraj Ud Din Hura, " Genetic Analysis, Health Issues and Consanguineous Marriage in Muslim Community , International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 4, Issue 2, pp.100-107, January-February-2018.