An Efficient Glaucoma Screening Using CDR From 2-D Retinal Fundus Images

Authors

  • M.Kezia  M. Tech, Department of Electronics and Communication, JNTUA, Andhra Pradesh, India

Keywords:

Glaucoma screening, super pixel classificaton, optic disc segmentation, optic cup segmentation, cup to disc ratio(CDR) .

Abstract

Glaucoma is the second leading cause of blindness all over the world. Eye’s optic nerve will be damaged as the result of glaucoma. Patients are also unaware of the disease because of its slow progression with very few symptoms. So detecting the disease in time is very important to avoid irreversible blindness. Automated optic nerve head (ONH) assessment from 2-D retinal fundus images is more promising for low-cost glaucoma screening. In this paper, super pixels classification based segmentation method is used for optic disc and optic cup boundary estimation. Subsequently, the CDR for testing fundus eye image is computed. The proposed method achieves good accuracy in large-scale population-based glaucoma screening.

References

  1. H. A. Quigley and A. T. Broman, "The number of people with glaucoma worldwide in 2010 and 2020," Br. J. Ophthalmol., vol. 90, no. 3, pp. 262-267, 2006.
  2. J. Meier et al., "Effects of preprocessing eye fundus images on appearance based glaucoma classification," in Proc. 12th Int. Conf. Comput. Anal.Images Patterns, 2007, pp. 165?172.
  3. R. Bock et al., "Classifying glaucoma with image-based features from fundus photographs," in Proc. Annu. Pattern Recog. Symp. German Assoc. Pattern Recog., 2007, pp. 355?364.
  4. R. Bock et al., "Glaucoma risk index: Automated glaucoma detection from color fundus images," Med. Image Anal., vol. 14, pp. 471?481,2010.
  5. G. D. Joshi, J. Sivaswamy, and S. R. Krishnadas, "Optic disk and cup segmentation from monocular color retinal images for glaucoma assessment," IEEE Trans. Med. Imag., vol. 30, no. 6, pp. 1192?1205, Jun. 2011.
  6. T. Damms and F. Dannheim, "Sensitivity and specificity of optic disc parameters in chronic glaucoma," Invest. Ophth. Vis. Sci., vol. 34, pp. 2246?2250, 1993.
  7. D. Michael and O. D. Hancox, "Optic disc size, an important consideration in the glaucoma evaluation," Clin. Eye Vis. Care, vol. 11, pp. 59?62, 1999.
  8. N. Harizman, C. Oliveira, A. Chiang, C. Tello, M. Marmor, R. Ritch, and J. M. Liebmann, "The ISNT rule and differentiation of normal from glaucomatous eyes," Arch. Ophthalmol., vol. 124, pp. 1579?1583, 2006.
  9. J. B. Jonas, M. C. Fernandez, and G. O. Naumann, "Glaucomatous parapapillary atrophy occurrence and correlations," Arch. Ophthalmol., vol. 110, pp. 214?222, 1992.
  10. R. R. Allingham, K. F. Damji, S. Freedman, S. E. Moroi, and G. Shafranov, Shields’ Textbook of Glaucoma, 5th ed. Philadelphia, PA: Lippincott Williams Wilkins, 2005.
  11. J. Xu, O. Chutatape, E. Sung, C. Zheng, and P. C. T. Kuan, "Optic disk feature extraction via modified deformable model technique for glaucoma analysis," Pattern Recognit., vol. 40, pp. 2063?2076,2007.
  12. M. D. Abr?moff, W. L. M. Alward, E. C. Greenlee, L. Shuba, C. Y. Kim, J. H. Fingert, and Y. H. Kwon, "Automated segmentation of theoptic disc from stereo color photographs using physiologically plausible features," Invest. Ophthalmol. Vis. Sci., vol. 48, pp. 1665?1673, 2007.
  13. Z. Hu,M. D. Abr?moff, Y. H. Kwon, K. Lee, andM. K. Garvin, "Automated segmentation of neural canal opening and optic cup in 3-d spectral optical coherence tomography volumes of the optic nerve head," Invest. Ophthalmol. Vis. Sci., vol. 51, pp. 5708?5717, 2010.
  14. M.D.Abr?moff, K. Lee, M. Niemeijer,W. L.M.Alward, E. Greenlee, M. Garvin, M. Sonka, and Y. H. Kwon, "Automated segmentation of the cup and rim from spectral domain oct of the optic nerve head," Invest. Ophthalmol. Vis. Sci., vol. 50, pp. 5778?5784, 2009.
  15. K. Stapor, A. Sacutewitonski, R. Chrastek, and G. Michelson, "Segmentation of fundus eye images using methods of mathematical morphology for glaucoma diagnosis," in Proc. Int. Conf. Comput. Sci., 2004, pp. 41?48.
  16. N. Inoue, K. Yanashima, K. Magatani, and T. Kurihara, "Development of a simple diagnostic method for the glaucoma using ocular fundus pictures," in Int. Conf. IEEE Eng. Med. Biol. Soc., 2005, pp. 3355?3358.
  17. D. W. K. Wong, J. Liu, J. H. Lim, X. Jia, H. Li, F. Yin, and T. Y. Wong, "Level-set based automatic cup-to-disc ratio determination using retinal fundus images in argali," Proc. Int. Conf. IEEE Eng. Med. Biol. Soc., pp. 2266?2269, 2008.
  18. Y. Hatanaka, A. Noudo, C. Muramatsu, A. Sawada, T. Hara, T. Yamamoto, and H. Fujita, "Automatic measurement of vertical cup-to disc ratio on retinal fundus images," in Proc. Int. Conf. Med. Biometrics,2010, pp. 64?72.
  19. X. Zhu and R. M. Rangayyan, "Detection of the optic disc in imagesof the retina using the hough transform," in Int. Conf. IEEE Eng. Med.Biol. Soc., 2008, pp. 3546?3549.
  20. A. Aquino, M. Gegundez-Arias, and D. Marin, "Detecting the optic disc boundary in digital fundus images using morphological, edge detection, and feature extraction techniques," IEEE Trans. Med. Imag.,vol. 29, no. 11, pp. 1860?1869, Nov. 2010.
  21. J. Cheng, J. Liu, D. W. K. Wong, F. Yin, C. Cheung, M. Baskaran,T. Aung, and T. Y. Wong, "Automatic optic disc segmentation with peripapillary atrophy elimination," in Int. Conf. IEEE Eng. in Med. Biol. Soc., 2011, pp. 6624?6627.
  22. J. Lowell, A. Hunter, D. Steel, A. Basu, R. Ryder, E. Fletcher, and L.Kennedy, "Optic nerve head segmentation," IEEE Trans. Med. Imag.,vol. 23, no. 2, pp. 256?264, Feb. 2004.
  23. Z. Zhang, J. Liu, N. S. Cherian, Y. Sun, J. H. Lim, W. K.Wong, N. M. Tan, S. Lu, H. Li, and T. Y. Wong, "Convex hull based neuro-retinal optic cup ellipse optimization in glaucoma diagnosis," in Int. Conf.IEEE Eng. Med. Biol. Soc., 2009, pp. 1441?1444.
  24. F. Yin, J. Liu, S. H. Ong, Y. Sun, D. W. K. Wong, N. M. Tan, C.Cheung, M. Baskaran, T. Aung, and T. Y. Wong, "Model-based optic nerve head segmentation on retinal fundus images," in Int. Conf. IEEE Eng. Med. Biol. Soc., 2011, pp. 2626?2629.
  25. L. Tang, M. K. Garvin,Y.H.Kwon, andM.D.Abr?moff, "Segmentation of optic nerve head rim in color fundus photographs by probability based active shape model," in ARVO, 2012.
  26. D. W. K. Wong, J. Liu, N. M. Tan, F. Yin, B. H. Lee, and T. Y. Wong, "Learning-based approach for the automatic detection of the optic disc in digital retinal fundus photographs," in Int. Conf. IEEE Eng. Med.
  27. F. Yin, J. Liu, S. H. Ong, Y. Sun, D. W. K. Wong, N. M. Tan, C.Cheung, M. Baskaran, T. Aung, and T. Y. Wong, "Model-based optic nerve head segmentation on retinal fundus images," in Int. Conf. IEEE Eng. Med. Biol. Soc., 2011, pp. 2626?2629.
  28. J. Cheng, J. Liu, D. W. K. Wong, F. Yin, C. Cheung, M. Baskaran,T. Aung, and T. Y. Wong, "Automatic optic disc segmentation with peripapillary atrophy elimination," in Int. Conf. IEEE Eng. in Med Biol. Soc., 2011, pp. 6624?6627.
  29. J. A. Giaconi, S. K. Law, A. L. Coleman, and J. Caprioli, Pearls of Glaucoma Management. New York: Springer, 2010.
  30. R. Achanta, A. Shaji, K. Smith, A. Lucchi, P. Fua, and S. Susstrunk, "Slic superpixels compared to state-of-the-art superpixel methods," IEEE Trans. Pattern Anal. Mach. Intell., vol. 34, no. 11, pp. 2274?2281, Nov. 2012.
  31. J. Cheng, J. Liu, Y. Xu, D. W. K. Wong, B. H. Lee, C. Cheung, T.Aung, and T. Y. Wong, "Superpixel classification for initialization in model based optic disc segmentation," in Int. Conf. IEEE Eng. Med. Biol. Soc., 2012, pp. 1450?1453.?
  32. E. H. Adelson, C. H. Anderson, J. R. Bergen, P. J. Burt, and J. M. Ogden, "Pyramid methods in image processing," RCA Eng., vol. 29, no. 6, pp. 33?41, 1984.
  33. A. Fitzgibbon, M. Pilu, and R. B. Fisher, "Direct least squares fitting of ellipses," IEEE Trans. Pattern Anal. Mach. Intell., vol. 21, no. 5, pp. 476?480, May 1999.

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Published

2018-02-28

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Section

Research Articles

How to Cite

[1]
M.Kezia, " An Efficient Glaucoma Screening Using CDR From 2-D Retinal Fundus Images , International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 4, Issue 2, pp.1404-1412, January-February-2018.