Manuscript Number : IJSRST184134
A Versatile Approach for Synthesis of Various Pyrimidine Derivatives Clubbed with Pyrazolone Structure and Their Biological Activities
Authors(1) :-Amish P. Khamar Different pyrimidine derivatives clubbed with pyrazolone structure possessing a diversity of substituents in the 6-position have been synthesized and evaluated for Mycobacterium tuberculosis activities. Several compounds demonstrated IC90 ≤ 10 µg/mL and were found to be active against Mycobacterium tuberculosis strain Compound 8d was found to be most active compound in vitro with IC90 of 1.53.
Amish P. Khamar Pyrazolopyrimidines, Antitubercular Activity, Antimycobacterial Activity, MABA Assay. Publication Details
Published in : Volume 3 | Issue 1 | January-February 2017 Article Preview
Arts, Science & R. A. Patel Commerce College, Bhadran, Gujarat, India
Date of Publication : 2017-02-28
License: This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 658-665
Manuscript Number : IJSRST184134
Publisher : Technoscience Academy
Journal URL : https://ijsrst.com/IJSRST184134
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