A Swift, Expedient and Solvent Less Synthesis of Highly Diversified 1,2,4-Triazolo [1,5-A] Pyrimidines Bearing Pyridine Scaffold

Authors

  • Dipak C Patel  The H. N. S. B. Ltd. Science College, Himmatnagar, Gujarat, India

Keywords:

1,2,4-Triazolo [1,5-A] Pyrimidines, Pyridine, Biginelli, Aminoazoles, Analytical Techniques

Abstract

The biological importance of 1,2,4-triazolo[1,5-a]pyrimidines is well documented. Over the years, various substituted derivatives of these heterocycles have shown utility against a range of biological targets. A, synthesis of 1,2,4-triazolo[1,5-a]pyrimidines bearing pyridine scaffold is based on the Biginelli like cyclocondensation of aromatic aldehydes and acetoacetamide with aminoazoles containing a guanidine fragment. The structures of all the newly synthesized compounds (4a-t) were elucidated by various analytical techniques like FT-IR spectroscopy, mass spectrometry and 1H NMR spectroscopy.

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International Journal of Scientific Research in Science and Technology

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Published

2017-01-30

Issue

Volume 3, Issue 1, January-February-2017

Section

Research Articles

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How to Cite

[1]
Dipak C Patel, " A Swift, Expedient and Solvent Less Synthesis of Highly Diversified 1,2,4-Triazolo [1,5-A] Pyrimidines Bearing Pyridine Scaffold, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 1, pp.666-673, January-February-2017.