Antibacterial and Antifungal Activity of Leaf Extracts of Pedalium murex L.

Authors

  • S. Aruljothi  Department of Botany, Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India
  • P. Vijayarengan  Department of Botany, Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India

Keywords:

Antimicrobial activity, Pedalium murex, MIC, MBC and MFC

Abstract

Pedalium murex Linn, commonly called Gokhru a member of family Pedaliaceae. The antimicrobial activity of Pedalium murex leaves were extracted successively with different solvents viz., petroleum ether, chloroform, ethyl acetate and methanol and screened for their antimicrobial activity against Gram positive bacteria: Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, Gram negative bacteria : Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and Vibrio cholera and fungal species: Candida albicans, C. Guillurmondii and C.glabrata by using Disc diffusion method. Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were also determined in the present research. The methanol leaf extract of Pedalium murex showed the highest antimicrobial activity against all the bacterial and fungal stains tested than the other extracts. The mean zones of inhibition produced by the extracts in Agar diffusion assays against the tested bacterial strains were ranged from 7.0 to 26.8 mm. The highest mean zone of inhibition (26.8 mm) was observed in the methanol extracts of Pedalium murex against the bacteria Staphylococcus aureus. The MIC values were between 7.81 and 250 µg/ml, MBC values:15.62 and 500 µg/ml and MFC values: 31.25 and 500 µg/ml were also recorded. From the above findings, we concluded that the methanolic leaf extract of Pedalium murex exhibited their antimicrobial potential which will be needed to isolate and characterize the compounds.

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International Journal of Scientific Research in Science and Technology

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Published

2018-02-28

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Volume 4, Issue 2, January-February-2018

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Research Articles

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How to Cite

[1]
S. Aruljothi, P. Vijayarengan, " Antibacterial and Antifungal Activity of Leaf Extracts of Pedalium murex L., International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 4, Issue 2, pp.450-456, January-February-2018.