Manuscript Number : IJSRST1845141
Antibacterial Activity of Marine Fungi Against Veterinary Based Clinical Pathogens
Authors(8) :-G. Anuhya, Ch. Koteswara Rao, G. Samuel, V. Jyostna, B. Bodaiah , C. Uma, I. Karthika Lakshmi,
P. Sudhakar Marine fungal metabolites are bioactive compounds develop and inhibit the growth of microbial and clinical pathogens. So, the Present study was focussed on potentiality of gaps-1 and gaps-2 against standard antibiotic tetracycline by their bioactivity to fetch out the veterinary medicine that are used by the bovine and poultry farmers. Bioactive metabolites were extracted from marine fungal isolates (GAPS-1 and GAPS-2) through solvent extraction. Potency of metabolite was determined by antibacterial assay and MIC (minimum inhibitory concentration) against Clinical pathogens like Escherichia coli, Klebsiella, Pasteurella multocida using standard antibiotic tetracycline as a standard. Fungal extracts of (GAPS-1 and GAPS-2) are effectively extracted in Ethyl acetate, when compared to chloroform, hexane and petroleum either respectively, both extracts had showed a prominence antibacterial activity on all test organisms and MIC of both extracts starts from 500µg where as standard antibiotic tetracycline starts from 250µg. Since both fungal isolates revealed significant effect on clinical pathogens indicating the potentiality of marine environment in producing alternatives of chemically synthesizing standard antibiotics.
G. Anuhya Marine fungi, antibacterial assay, Clinical pathogens, MIC, Antibiotics. Publication Details
Published in : Volume 4 | Issue 5 | March-April 2018 Article Preview
Department of Biotechnology, Acharya Nagarjuna University, Andhra Pradesh, India
Ch. Koteswara Rao
Department of Commerce and business Administration, Acharya Nagarjuna University, Andhra Pradesh, India
G. Samuel
Poultry farmer, Dharanikota, Guntur, Andhra Pradesh, India
V. Jyostna
Department of Biotechnology, Acharya Nagarjuna University, Andhra Pradesh, India
B. Bodaiah
Department of Biotechnology, Acharya Nagarjuna University, Andhra Pradesh, India
C. Uma
AD of Department of Epidemiology, Animal Husbandary, Vijayawada, Andhra Pradesh, India
I. Karthika Lakshmi
AD of Department of Epidemiology, Animal Husbandary, Vijayawada, Andhra Pradesh, India
P. Sudhakar
Department of Biotechnology, Acharya Nagarjuna University, Andhra Pradesh, India
Date of Publication : 2018-04-30
License: This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 742-746
Manuscript Number : IJSRST1845141
Publisher : Technoscience Academy
Journal URL : https://ijsrst.com/IJSRST1845141
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