Synthesis, Characterization and Biological Activity of Some Novel Phenylalanine Derivatives of Nucleobase

Authors

  • Dr. G. D. Acharya  R. R. Mehta College of Science and C. L. Parikh College of Commerce, Palanpur, Gujarat, India
  • Dhaval V. Bhanotra  R. R. Mehta College of Science and C. L. Parikh College of Commerce, Palanpur, Gujarat, India
  • Govind R. Varde*  R. R. Mehta College of Science and C. L. Parikh College of Commerce, Palanpur, Gujarat, India
  • Bhavesh S. Varavadiya  R. R. Mehta College of Science and C. L. Parikh College of Commerce, Palanpur, Gujarat, India
  • Milan A. Sharda  R. R. Mehta College of Science and C. L. Parikh College of Commerce, Palanpur, Gujarat, India

Keywords:

Nucleobase , Phenylalanine, Amino acid , Antimicrobial activity , Antifungal activity , Antibacterial activity.

Abstract

With an objective to synthesize compounds with anti-cancer and other anti-microbial properties ,a systematically planned organic synthesis has been carried out. The organic compounds were synthesized from reacting partner in solvent phase in microwave method. Nucleobase had been a very significant heterocyclic and also amino acids are having highly significant physiological activity. The synthesized compounds were characterized by sensitive instrumental method like. Mass spectra,13C NMR. Infra-Red spectra, Uv spectra etc. Their structures were thus confirmed by different physicochemical methods.

References

  1. David.L. Nelson, Michael M.cox :Lehninger Principles of biochemistry. Fourth edition.
  2. Jeremy M.Berg, John L. Tymoczko, Lubert Stryer : Biochemistry 5th edition
  3. U.Satyanarayana, U.chakrapani : Biochemistry 4thedition.
  4. Michael M Cox, David. L. Nelson :Principle of biochemisty 5th edition.
  5. Vinay Prabha Sharma :Essentials of Bio-Organic chemistry.
  6. Dr. K. Rambabu: Textbook of biochemistry 1st edition 2007.
  7. Robert k.Murray, Daryl k.Granner, Peter A.mayes, Victor W. Rodwell, Harper's Biochemistry, 25 th edition.
  8. Mary K. Campbell: Biochemistry 3rd edition 1995.
  9. P. S .Kalsi, Spectroscopy Of Organic Compound. 6th Edition, New Age International Publication.
  10. Spectroscopy by Lampman, Pavia, Kriz, Vyvyan. 4th Edition.
  11. W.Robert and E.G.scott “Diagnostic microbiology” The C.V.Mocby co, Saint Louis. 2 nd edition pp.318 (1966).
  12. C.Robert “Medical microbiology” ELBS, Livingston,11th edition. PP.815 and PP.901 (1970).
  13. Rakesh.J.Patel and Kiran.r. patel Experimental microbiology.

International Journal of Scientific Research in Science and Technology

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Published

2018-04-30

Issue

Volume 4, Issue 5, March-April-2018

Section

Research Articles

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Copyright (c) IJSRST

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How to Cite

[1]
Dr. G. D. Acharya, Dhaval V. Bhanotra, Govind R. Varde*, Bhavesh S. Varavadiya, Milan A. Sharda, " Synthesis, Characterization and Biological Activity of Some Novel Phenylalanine Derivatives of Nucleobase, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 4, Issue 5, pp.822-827, March-April-2018.