Comparative Antibacterial and Antioxidant activity from root and fruit extracts of Momordica charantia L. and Momordica dioica Roxb

Authors

  • M. Anjamma  Department of Botany, University College of Science, Saifabad, Osmania University, Hyderabad, Telangana, India
  • N. Lakshmi Bhavani  Department of Botany, University College of Science, Saifabad, Osmania University, Hyderabad, Telangana, India

Keywords:

Momordica charantia, Momordica dioica, Root, Fruit extracts, Antibacterial, Antioxidant activity.

Abstract

Momordica charantia L. and Momordica dioica Roxb are perennial climbing creepers belonging to the family Cucurbitaceae and generally used as vegetables in Southern India, Bengal, Maharashtra and Madhya Pradesh. In the present study the methanolic extract of fruits and roots of M. charantia and M. dioica were analyzed for the presence of different phytochemical constituents. The extracts were also used for screening of antimicrobial and antioxidant properties. The activities of the compounds were compared with standard strain for antibacterial properties and the solvent extracts indicated that the compounds are active in exhibiting antibacterial role. Fruits and roots of M. charantia and M. dioica exhibited potent antioxidant activity by inhibiting DPPH free radicals which indicates the root and fruit extracts are very good source of natural antioxidant agent. The antibacterial activity of fruit extract was more than the root extract for both gram negative and gram positive bacteria. M. charantia and M. dioica exhibited potent antioxidant activity by inhibiting DPPH free radicals which indicate the fruit and root extracts of both plant materials can be used as an accessible source of natural antioxidant agent.

References

  1. Sabir MS, Ahmad DS, Hussain IM and Tahir KM, 2007. Antibacterial activity of Elaeagnus umbellate (Thumb.) a medicinal plant from Pakstan. Saudi Med J, 28(2): 259-263.
  2. Joseph JK, 2005. Studies on ecogeography and genetic diversity of the genus Momordica L. in India. M. Sc. Dissertation submitted to Mahatma Gandhi University, Kottayam, Kerala, India.
  3. Bawara B, Dixit M, Chauhan NS, Dixit VK and Saraf DK, 2010. Phyto-Pharmacology of Momordica dioica Roxb. ex. wild: A Review. International Journal of Phytomedicine, 2:01-09.
  4. Ram D, Kumar S, Verma A and Rai M, 2004. Variability analysis of underutilized nutritive vegetable Kartoli: Indian collection. Cucurbit Genetics Cooperative Report, 27: 66-68.
  5. Aberoumand A and Deokule SS, 2009. Studies on nutritional values of some wild edible plants from Iran and India. Pakistan Journal of Nutrition, 8: 26-31.
  6. Kumar U and Prajapati ND. Agro's, 2003. Dictionary of Medicinal Plants. Agrobios (India), Agrohouse Jodhpur, India, pp 216.
  7. Jain A and Singhai AK, 2010. Effect of Momordica dioica Roxb. on gentamicin model of acute renal failure. Natural Products Research, 24:1379-1389.
  8. Ahmed I, Lakhani MS, Gillett M, et al. 2001. "Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (Karela) fruit extract in streptozotocin-induced diabetic rats." Diabetes Res Clin Pract, 51(3):155–61.
  9. Takemoto DJ, 1983. "Purification and characterization of a cytostatic factor with anti-viral activity from the bitter melon." Prep Biochem, 13(4): 371–93.
  10. Rastogi T, Bhutda V, Moon K, Aswar PB and Khadabad SS, 2009. Comparative Studies on Anthelmintic Activity of Moringa Oleifera and Vitex Negundo. Asian J Rese Chem, 2(2):181-82.
  11. Yadav P and Singh R, 2011. A Review on Anthelmintic drugs and their future scope. Int J Pharm Sci, 3(3):17-21.
  12. Mali RG, Mahajan S and Patil KS, 2005. Anthelmintic activity of root bark of Capparis spinosa. Ind J Nat Prod, 21:50-51.
  13. Nagasawa H, Watanabe K, Inatomi H et al., 2002. "Effects of bitter melon (Momordica charantia) or ginger rhizome (Zingiber offifinale Rosc.) on spontaneous mammary tumorigenesis in SHN mice." Am J Clin Med, 30(2–3): 195–205.
  14. Grover JK and Yadav SP, 2004. Pharmacological actions and potential uses of Momordica charantia: A review. J Ethnopharmacol, 93: 123–132.
  15. Leelaprakash G, Caroline Rose J, Gowtham BM, Pradeep Krishna Javvaji and Shivram Prasad, 2011. A In vitro, antimicrobial and antioxidant activity of Momordica charantia leaves. Pharmacophore, 2 (4), 244-252.
  16. Jagessar RC, Mohamed A and Gomes G, 2008. An evaluation of the Antibacterial and Antifungal activity of leaf extracts of Momordica Charantia against Candida albicans, Staphylococcus aureus and Escherichia coli. Nature and Science, 6(1).
  17. Ilango K, Maharajan G and Narasimhan S, 2012. Preliminary Phytochemical Screening and Antibacterial Activity of Fruit Pulp of Momordica dioica Roxb. (Cucurbitaceae) African Journal of Basic & Applied Sciences, 4 (1): 12-15.
  18. Vani P, Sreekanth D, Manjula P, Keerthi B, Kistamma S, Mohan B, Narshimha Reddy and Mohan Ch, 2016. Phytochemical investigation, antibacterial activity and antioxidant activity of the endangered tree Commiphora wightii (Arn.) Bhandari, Journal of Pharmacognosy and Phytochemistry, 5(5): 21-25.
  19. Bumrela Shrinivas, Samleti Anil, Melisa Parera and Manisha Saxena, 2009. Evaluation of antimicrobial and antioxidant properties of Momordica dioica Roxb. (Ex Willd). Journal of Pharmacy Research, 2(6), 1075-1078.
  20. Vani P, Kistamma S, Srinivas Reddy K, Narshimha Reddy A and Mohan Ch, 2016. Antibacterial activity, antioxidant activity and micropropagation of Gymnema sylvestre R.Br. a valuable medicinal plant. Journal of Pharmacognosy and Phytochemistry, 5(2): 207-210.
  21. Mohan Ch, Sridhar S, Mohan B, SB. Krishnaveni and S. Karnakar Reddy, 2015. Antibacterial activity and phytochemical screening of Hemidesmus indicus L. B. BR. Int. J. Pure App. Biosci. 3 (2): 221-225.

International Journal of Scientific Research in Science and Technology

Downloads

Published

2018-04-30

Issue

Volume 4, Issue 5, March-April-2018

Section

Research Articles

License

Copyright (c) IJSRST

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
M. Anjamma, N. Lakshmi Bhavani, " Comparative Antibacterial and Antioxidant activity from root and fruit extracts of Momordica charantia L. and Momordica dioica Roxb, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 4, Issue 5, pp.1710-1716, March-April-2018.