Biosynthesis of CuO nanoparticles using aqueous extract of Ziziphus mauritiana L. leaves and their Catalytic performance for the 5-aryl-1,2,4-triazolidine-3-thione derivatives synthesis

Authors(3) :-Shreyas. S. Pansambal , Suresh. K. Ghotekar, Rajeshwari Ozaa Keshav. K. Deshmukh

Copper oxide (CuO) nanoparticles (NPs) were synthesized by biological method using aqueous extract of Ziziphus mauritiana L. leaves as a reducing and stabilizing agent. The merits of this procedure are an easy operation, use of cheap, nontoxic and environmentally benign precursors. The structural and morphological properties of the as-prepared nanocatalyst were done by using XRD, SEM, EDX, TEM and BET-surface area. Furthermore, these NPs are used as an effective nanocatalyst for simple and one-pot synthesis of 5-aryl-1,2,4-triazolidine-3-thione derivatives. The reaction steps including imine formation, cyclization, condensation and aromatization occurs, without use of any oxidizing or reducing reagents. The present methodology offers several remarkable merits such as shorter reaction time, mild reaction conditions, excellent yield, simplicity, safer reaction pathway, easy workup and recyclable catalyst without any significant loss in catalytic activity and can be used for large scale synthesis. Hence, this study describing the synthesis of CuO NPs by effective biogenic method followed by the investigation of potent catalytic activities may be useful for nanochemistry research opening new horizons in this field.

Authors and Affiliations

Shreyas. S. Pansambal
S. N. Arts, D. J. Malpani Commerce & B. N. Sarda Science College, Sangamner, Maharashtra, India
Suresh. K. Ghotekar
Department of Applied Sciences and Humanities, G. M. Vedak Institute of Technology, Tala, University of Mumbai, Maharashtra, India
Rajeshwari Ozaa Keshav. K. Deshmukh
S. N. Arts, D. J. Malpani Commerce & B. N. Sarda Science College, Sangamner, Maharashtra, India

Nanotechnology, Ziziphus mauritiana L., CuONPs, Recyclable catalyst.

  1. C. Deraedt and D. Astruc, Acc. Chem. Res., 2014, 47, 494-503.
  2. L. Luza, A. Gual and J. Dupont, ChemCatChem, 2014, 6, 702-710.
  3. E. Shahbazali, V. Hessel, T. Noël and Q. Wang, Nanotechnol. Rev., 2014, 3, 1-23.
  4. M. A. Bhosale and B. M. Bhanage, 2015, 19, 708-727.
  5. B. S. Takale, M. Bao, Y. Yamamoto, A. I. Almansour, N. Arumugam and R. S. Kumar, Synlett, 2015, 26, 2355-2380.
  6. D. Rehana, D. Mahendiran, R. S. Kumar and A. K. Rahiman, Biomed. Pharmacother., 2017, 89, 1067-1077.
  7. M. B. Gawande, A. Goswami, F. X. Felpin, T. Asefa, X. Huang, R. Silva, X. Zou, R. Zboril and R. S. Varma, Chem. Rev., 2016, 116, 3722-3811.
  8. A. Hernández Battez, R. González, J. L. Viesca, J. E. Fernández, J. M. Díaz Fernández, A. Machado, R. Chou and J. Riba, Wear, 2008, 265, 422-428.
  9. M. Frietsch, F. Zudock, J. Goschnick and M. Bruns, Sensors Actuators, B Chem., 2000, 65, 379-381.
  10. M. T. Keßler, S. Robke, S. Sahler and M. H. G. Prechtl, Catal. Sci. Technol., 2014, 4, 102-108.
  11. H. Wang, J. Z. Xu, J. J. Zhu and H. Y. Chen, J. Cryst. Growth, 2002, 244, 88-94.
  12. R. V. Kumar, Y. Diamant and A. Gedanken, Chem. Mater., 2000, 12, 2301-2305.
  13. K. Borgohain, J. B. Singh, M. V. Rama Rao, T. Shripathi and S. Mahamuni, Phys. Rev. B, 2000, 61, 11093-11096.
  14. A. A. Eliseev and A. V Lukashin, J. Mater. Res. Innov., 2000, 3, 308-312.
  15. M. Salavati-Niasari and F. Davar, Mater. Lett., 2009, 63, 441-443.
  16. A. Savale, S. Ghotekar and O. Pansambal, Shreyas and Pardeshi, J. Bacteriol. Mycol. Open Access, 2017, 5, 1-5.
  17. S. K. Ghotekar, S. N. Pande, S. S. Pansambal, S. Dnyaneshwar, K. M. Mahale, B. Sonawane and S. N. Arts, WORLD J. Pharm. Pharm. Sci., 2015, 4, 1304-1312.
  18. S. Ghotekar, A. Savale and S. Pansambal, J. Water Environ. Nanotechnol., 2018, 3, 95-105.
  19. M. Maruthupandy, Y. Zuo, J. S. Chen, J. M. Song, H. L. Niu, C. J. Mao, S. Y. Zhang and Y. H. Shen, Appl. Surf. Sci., 2017, 397, 167-174.
  20. K. Lingaraju, H. Raja Naika, K. Manjunath, G. Nagaraju, D. Suresh and H. Nagabhushana, Acta Metall. Sin. (English Lett., 2015, 28, 1134-1140.
  21. Y. B. Aher, G. H. Jain, G. E. Patil, A. R. Savale, K. Suresh, D. M. Pore, S. S. Pansambal and K. K. Deshmukh, Int. J. Mol. Clin. Microbiol., 2017, 7, 776-786.
  22. J. K. Sharma, M. S. Akhtar, S. Ameen, P. Srivastava and G. Singh, J. Alloys Compd., 2015, 632, 321-325.
  23. S. Gunalan, R. Sivaraj and R. Venckatesh, Spectrochim. Acta Part A Mol. Biomol. Spectrosc., 2012, 97, 1140-1144.
  24. R. Sankar, P. Manikandan, V. Malarvizhi, T. Fathima, K. S. Shivashangari and V. Ravikumar, Spectrochim. Acta - Part A Mol. Biomol. Spectrosc., 2014, 121, 746-750.
  25. G. Jayakumarai, C. Gokulpriya, R. Sudhapriya, G. Sharmila and C. Muthukumaran, Appl. Nanosci., 2015, 5, 1017-1021.
  26. S. Pansambal, K. Deshmukh, A. Savale, S. Ghotekar, O. Pardeshi, G. Jain, Y. Aher and D. Pore, J Nanostruct.
  27. J. M. Kane, M. W. Dudley, S. M. Sorensen and F. P. Miller, J. Med. Chem., 1988, 31, 1253-1258.
  28. R. Chelamalla, V. Akena and S. Manda, Med. Chem. Res., 2017, 26, 1359-1366.
  29. A. D. Sonawane, N. D. Rode, L. Nawale, R. R. Joshi, A. Joshi, A. P. Likhite, D. Sarkar and C. R. Centre, Chem. Biol. drug Des., 2017, 90, 200-209.
  30. H. A. Burch and W. O. Smith, J. Med. Chem., 1966, 9, 405-408.
  31. A. Foroumadi, S. Mansouri, Z. Kiani and A. Rahmani, Eur. J. Med. Chem., 2003, 38, 851-854.
  32. H. L. Yale and J. J. Piala, J. Med. Chem., 1966, 9, 42-46.
  33. G. Palareti, C. Legnani, B. Cosmi, E. Antonucci, N. Erba, D. Poli, S. Testa and A. Tosetto, Int. J. Lab. Hematol., 2016, 38, 42-49.
  34. J. D. Patil and D. M. Pore, RSC Adv., 2014, 4, 14314.
  35. S. N. Korade, J. D. Patil and D. M. Pore, Monatshefte für Chemie - Chem. Mon., 2016, 147, 2143-2149.
  36. R. Ramesh and A. Lalitha, RSC Adv., 2015, 5, 51188-51192.
  37. D. M. Pore, P. G. Hegade, M. M. Mane and J. D. Patil, RSC Adv., 2013, 3, 25723.
  38. S. N. Maddila, S. Maddila, K. K. Gangu, W. E. van Zyl and S. B. Jonnalagadda, J. Fluor. Chem., 2017, 195, 79-84.
  39. K. K. Gangu, S. Maddila, S. N. Maddila and S. B. Jonnalagadda, Res. Chem. Intermed., 2017, 43, 1793-1811.
  40. M. M. Mane and D. M. Pore, Tetrahedron Lett., 2014, 55, 6601-6604.
  41. D. A. Mali and V. N. Telvekar, Synth. Commun., 2017, 47, 324-329.
  42. P. B. Patil, J. D. Patil, S. N. Korade, S. D. Kshirsagar, S. P. Govindwar and D. M. Pore, Res. Chem. Intermed., 2016, 42, 4171-4180.
  43. S. Pansambal, S. Gavande, S. Ghotekar, R. Oza and K. Deshmukh, Int. J. Sci. Res. Sci. Technol., 2017, 3, 1388-1392.

Publication Details

Published in : Volume 5 | Issue 4 | January 2019
Date of Publication : 2019-01-04
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 122-128
Manuscript Number : IJSRST195427
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Shreyas. S. Pansambal , Suresh. K. Ghotekar, Rajeshwari Ozaa Keshav. K. Deshmukh, " Biosynthesis of CuO nanoparticles using aqueous extract of Ziziphus mauritiana L. leaves and their Catalytic performance for the 5-aryl-1,2,4-triazolidine-3-thione derivatives synthesis", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 5, Issue 4, pp.122-128, January-2019.
Journal URL :

Article Preview