Formulation and Evaluation of Herbal Gel Containing Solanum Nigrum Extract

Authors(5) :-Dr. Nagoba Shivappa N., Sonkamble Pallavi S., Sakhare Ram S. , Wadulkar Raghunath D., Swami Avinash B.

The aim of present study was to formulate and evaluate herbal gel containing Solanum nigrum extract for prevention of wound healing. Topical gel formulation was designed by using Solanum nigrum extract as API and HPMC E5 as a gelling agent. The herbaceous plant Solanum nigrum (kamuni) reported for healing action and newer research studies and methodologies are being carried to find active chemical constituents which not only promise fast healing but also will reduce the complication and cost. Extracts of this medicinal plant are useful in the treatment of several health problems such as bacterial infections, ulcer, cancer, tuberculosis, arthritis and inflammatory. The plant Solanum nigrum (kamuni) leaves is the best traditional medicine for the study of wound healing activity. The concept of wound healing is changing from day to day. Ayurveda is the richest source of plant drugs for management of wounds and Solanum nigrum L. is one such. The plant is used as haemostatic and wound healing agent from ethno pharmacological point of view. The prepared gel was characterized for their physicochemical parameters i.e., preliminary phytochemical analysis, quantitative analysis, appearance, spreadability, pH, viscosity, in-vitro diffusion study and stability study.

Authors and Affiliations

Dr. Nagoba Shivappa N.
Associate Professor and Head, Department of Pharmaceutics, Channabasweshwar Pharmacy College, Kava Road, Latur, Maharashtra, India
Sonkamble Pallavi S.
Department of Pharmaceutics, Channabasweshwar Pharmacy College, Latur, Maharashtra, India
Sakhare Ram S.
Department of Pharmaceutics, Channabasweshwar Pharmacy College, Latur, Maharashtra, India
Wadulkar Raghunath D.
Department of Pharmaceutics, Channabasweshwar Pharmacy College, Latur, Maharashtra, India
Swami Avinash B.
Department of Pharmaceutics, Channabasweshwar Pharmacy College, Latur, Maharashtra, India

Solanum Nigrum, HPMC E5, Herbal Gel, Wound Healing

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Publication Details

Published in : Volume 6 | Issue 4 | July-August 2019
Date of Publication : 2019-08-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 83-91
Manuscript Number : IJSRST196415
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Dr. Nagoba Shivappa N., Sonkamble Pallavi S., Sakhare Ram S. , Wadulkar Raghunath D., Swami Avinash B., " Formulation and Evaluation of Herbal Gel Containing Solanum Nigrum Extract", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 6, Issue 4, pp.83-91, July-August-2019. Available at doi : https://doi.org/10.32628/IJSRST196415    
Journal URL : https://ijsrst.com/IJSRST196415
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