Sublingual Tablets : An Overview

Authors

  • Rohit S. Nikam  Arvind Gavali College of Pharmacy, Jaitapur, Dist - Statra, Maharashra, India
  • Rahul P. Jadhav  Rajarambapu College of Pharmacy, Kasegaon, Dist - Sangli, Maharashtra, India
  • Dr. Prakash D. Jadhav  Arvind Gavali College of Pharmacy, Jaitapur, Dist - Statra, Maharashra, India
  • Vishal D. Yadav  Arvind Gavali College of Pharmacy, Jaitapur, Dist - Statra, Maharashra, India

DOI:

https://doi.org//10.32628/IJSRST196520

Keywords:

Sublingual Tablets, Mucosa, Pregastric absorption, Drug Delivery, Oral Mucous Membrane

Abstract

Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route. Sublingual route is a rapid onset of action and better patient compliance than orally ingested tablets. Sublingual literally meaning is 'under the tongue', administrating substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue. Peroral administration of drug has disadvantages such as Hepatic first pass metabolism and enzymatic degradation within the GI tract that limits oral administration of certain classes of drug like peptides and proteins. So, other absorptive mucosa is considered as potential sites for drug administration. Trans-mucosal routes of drug delivery (i.e. the mucosal linings of the nasal, rectal, vaginal, ocular, and oral cavity) offer several advantages over peroral administration for systemic delivery. This review highlights the sublingual dosage forms for the treatment of migraine, advantages, Disadvantages, various evaluation parameters and commercially available sublingual dosage forms.

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International Journal of Scientific Research in Science and Technology

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Published

2019-10-30

Issue

Volume 6, Issue 5, September-October-2019

Section

Research Articles

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How to Cite

[1]
Rohit S. Nikam, Rahul P. Jadhav, Dr. Prakash D. Jadhav, Vishal D. Yadav, " Sublingual Tablets : An Overview, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 6, Issue 5, pp.181-187, September-October-2019. Available at doi : https://doi.org/10.32628/IJSRST196520