Study of antimicrobial and antifungal activities of some synthesized 2-(2-amino-1, 3-Oxazol-4-yl)-4-substitutednaphthalen-1-ol

Authors(2) :-Dasharath M. Chavhana, Shrikant S. Patil

New oxazole derivative of substitutednaphthol were ecofriendly and efficiently be synthesized like 2-(2-amino-1, 3-oxazol-4-yl)-4-substitutednaphthalen-1-ol by cyclization of 1-[2-(4-Substituted-1-hydroxynaphthalen-2-yl)-2-oxoethyl]thiocarbamide by utilizing elemental sulphur as a chief, easily available, non toxic catalyst. Some of these compounds were screen for their antimicrobial and antifungal activity against some selected microbe like C. albicans, A. niger, S. Typhi, E. coli, S. dysenteriae, K. pneumoniae, S. aureus by agar well diffusion assay method carried out. The compounds screen against selected microbe shows good results.

Authors and Affiliations

Dasharath M. Chavhana
Department of Chemistry, Indira Mahavidyalaya, Kalamb, Yavatmal, Maharashtra, India
Shrikant S. Patil
Professor and Director, Department of lifelong learning and Extension, Sant Gadge Baba Amravati University, Amravati, Maharashtra, India

Antimicrobial, antifungal, microbes, agar well diffusion assasy method.

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Publication Details

Published in : Volume 4 | Issue 1 | January-February 2018
Date of Publication : 2018-01-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 66-73
Manuscript Number : IJSRST4116
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Dasharath M. Chavhana, Shrikant S. Patil, " Study of antimicrobial and antifungal activities of some synthesized 2-(2-amino-1, 3-Oxazol-4-yl)-4-substitutednaphthalen-1-ol", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 4, Issue 1, pp.66-73 , January-February-2018.
Journal URL : https://ijsrst.com/IJSRST4116
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