Green Cellular Delivery of Copper Nanoparticle from Mirabilis Jalapa Flower Extract and Its Antipathogenic Activity

Authors

  • C R Rathi  Department of Biotechnology, Sree Narayana Guru College of Arts and Science, Coimbatore, Tamil Nadu, , India
  • S N Suresh  Department of Biotechnology, Sree Narayana Guru College of Arts and Science, Coimbatore, Tamil Nadu, , India

DOI:

https://doi.org//10.32628/IJSRST207478

Keywords:

Nanoparticles, Mirabilis jalapa, Antibacterial activity, UV-VIS spectroscopy, SEM, XRD.

Abstract

Bio friendly green modest synthesis of nanoparticles are the present research in the extremity of nanotechnology. This study has been undertaken to explore the determinants of copper nanoparticles from 1 mM CuSO4 solution through profuse concentration of aqueous flower extract of Mirabilis jalapa reducing besides immobilizing agent. The attribute of copper nanoparticles was studied by using UV-VIS spectroscopy SEM and XRD. The XRD spectrum of the copper nanoparticles established the presence of elemental copper signal. Green synthesized copper nanoparticles manifests the zone of inhibition against isolated human pathogenic (Streptococcus species, Bacillus species, Staphylococcus species, Klebsiella species and E. coli) bacteria. The analytical chassis contains the flower pigment betalain the natural food dye resources can efficiently use in the production of copper nanoparticles and it could be utilized in various fields in therapeutical and nanotechnology.

References

  1. Appendini P and Hotchkiss JH (2002). Review of antimicrobial food packaging. Innovative Food Science & Emerging Technologies 3(2)113-126.
  2. Bhatti, U. and Hanif. M. 2010. Validity of Capital Assets Pricing Model. Evidence from KSE-Pakistan. European Journal of Economics, Finance and Administrative Science, 3 (20). A comparative study of the cytotoxicity of silver-based dressings in monolayer cell, tissue explant, and animal models. Wound Repair and Regeneration 15(1) 94-104.
  3. Boateng JS, Matthews KH, Stevens HN and Eccleston GM (2008). Wound healing dressings and drug delivery systems: a review. Journal of Pharmaceutical Sciences 97(8) 2892-291.
  4. Castellano JJ, Shafii SM, Ko F, Donate G, Wright TE, Mannari RJ, Payne WG, Smith DJ and Robson MC (2007). Comparative evaluation of silver-containing antimicrobial dressing and drugs. International Wound Journal 4(2) 144-22.
  5. Danilczuk M, Lund A, Saldo J, Yamada H, Michalik J (2006). Conduction electron spin resonance of small silver particles. Spectrochimaca Acta Part A: Molecular and Biomolecular Spectroscopy 63(1) 189 - 91.
  6. Dimayuga, R E (1998). Antimicrobial activity of medicinal plants from Baja California Sur/Mexico. Pharmaceutical Biol 36:33-43.
  7. El-Rafie MH, Mohamed AA, Shaheen TI and Hebeish A (2010). Antimicrobial effect of silver nanoparticles produced by fungal process on cotton fabrics. Carbohydrate Polymers 80(3) 779-782. Feng QL, Wu J, Chen GQ, Cui FZ, Kim TN and Kim JO (2000).
  8. Fox CL and Modak SM (1974). Mechanism of silver sulfadiazine action on burn wound infections. Antimicrobial Agents and Chemotherapy 5(6) 582–588.
  9. Furno F, Morley KS, Wong B, Sharp BL, Arnold PL and Howdle SM (2004). Silver nanoparticles and polymeric medical devices: a new approach to prevention of infection? Journal of Antimicrobial Chemotherapy 54(6) 1019–1024.
  10. Gavhane AJ, Padmanabhan P, Kamble SP and Jangle SN (2012). Synthesis of silver nanoparticles using extract of Neem leaf and Triphala and evaluation of their antimicrobial activities. International Journal of Pharma and Bio Sciences 3(3) 88-100.
  11. Gong P, Li H, He X, Wang K, Hu J, Tan W, Zhang S and Yang X (2007). Preparation and antibacterial activity of Fe3O4@Ag nanoparticles. Nanotechnology 18(28) 604-611.
  12. Guggenbichler JP, Boswald M, Lugauer S and Krall T (1999). A new technology of micro dispersed silver in polyurethane induces antimicrobial activity in central venous catheters. Infection 27(1) 16-23.
  13. Gupta A and Silver S (1998). Silver as a biocide: will resistance become a problem? Nature Biotechnology 16(10) 888. Hussain SM, Hess KL, Gearhart JM, Geiss K and Schlager JJ (2005). In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicology In Vitro 19(7) 975-986.
  14. Ip M, Lui SL, Poon VKM, Lung I and Burd A (2006). Antimicrobial activities of silver dressings: an in vitro comparison. Journal of Medical Microbiology 55(1) 59-63.
  15. Jain P and Pradeep T (2005). Potential of silver nanoparticle-coated polyurethane foam as an antibacterial water filter. Biotechnology and Bioengineering 90(1) 59-63.
  16. Jia J, Duan YY, Wang SH, Zhang SF and Wang ZY (2007). Preparation and characterization of antibacterial silver-containing nanofibers for wound dressing applications. Journal of US-China Medical Science 4(2) 52–54.
  17. Kim JS, Kuk E, Yu KN, Kim JH, Park SJ, Lee HJ, Kim SH and Cho MH (2007). Antimicrobial effects of silver nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine 3(1) 95-101.
  18. Klueh U, Wagner V, Kelly S, Johnson A and Bryers JD (2000). Efficacy of silver coated fabric to prevent bacterial colonization and subsequent devicebased biofilm formation. Journal of Biomedical Materials Research Part B: Applied Biomaterials 53(6) 621-631.
  19. Kollef MH, Afessa B, Anzueto, A, Veremakis C, Kerr KM, Margolis BD, Craven DE, Roberts PR, Arroliga AC, Hubmayr RD, Restrepo MI, Auger WR and Schinner R (2008). Silver coated endotracheal tubes and incidence of ventilator-associated pneumonia. The Journal of the American Medical Association 300(7) 805-813.
  20. Kumar A, Vemula PK, Ajayan PM and John G (2008). Silver-nanoparticle-embedded antimicrobial paints based on vegetable oil. Nature Materials 7(3) 236-41.
  21. Leaper DJ and Durani P (2008). Topical antimicrobial therapy of chronic wounds healing by secondary intention using iodine products. International Wound Journal 5(2) 361-68.
  22. Li Y, Leung P, Yao L, Song QW and Newton E (2006). Antimicrobial effect of surgical masks coated with nanoparticles. Journal of Hospital Infection 62(1) 58-63.
  23. Lok CN, Ho CM, Chen R, He QY, Yu WY, Sun H, Kwong-Hang P, Chiu TJ and Che CM (2006). Proteomic analysis of the mode of antibacterial action of silver nanoparticles. Journal of Proteome Research 5(4) 916-924.
  24. Lok CN, Ho CM, Chen R, He QY, Yu WY, Sun H, Tam PK, Chiu J and Che CM (2007). Silver nanoparticles: partial oxidation and antibacterial activities. Journal of Biological Inorganic Chemistry 12(4) 527-534.
  25. Matsuura T, Abe Y, Sato K, Okamoto K, Ueshige M and Akagawa Y (1997). Prolonged antimicrobial effect of tissue conditioners containing silver zeolite. Journal of Dentistry 25(5) 373-377.
  26. Morones JR, Elechiguerra JL, Camacho A, Holt K, Kouri JB, Ramirez JT and Yacaman MJ (2005). The bactericidal effect of silver nanoparticles. Nanotechnology 16(10) 2346-2353.
  27. Nikawa H, Yamamoto Hamada T, Rahardjo MB and Murata Nakaando S (1997). Antifungal effect of zeolite-incorporated tissue conditioner against Candida albicans growth and/or acid production. Journal of Oral Rehabilitation 24(5) 350-357.
  28. Oberdorster G, Oberdorster E and Oberdorster J (2005). Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environmental Health Perspective 113(7) 823-939.
  29. Olson ME, Harmon BG and Kollef MH (2002). Silver-coated endotracheal tubes associated with reduced bacterial burden in the lungs of mechanically ventilated dogs. Chest Journal 121(3) 863-870.
  30. Ong S, Wu J, Moochhala SM, Tan M and Lu J (2008). Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties. Biomaterials 29(32) 4323-4332.
  31. Richard JW, Spencer BA, McCoy LF, Carina E, Washington J and Edgar P (2002). Acticoat versus silverlon: the truth. Journal of Burns Surgical Wound Care 1(1)11-20.
  32. Russell AD, Path FRC, Si FP and Hugo WB (1994). 7 Antimicrobial activity and action of silver. Progress in Medicinal Chemistry 31(1) 351-370.
  33. Shankar SS, Rai A, Ahmad A and Sastry M (2004). Rapid synthesis of Au, Ag and bimetallic Au core- Ag shell nanoparticles using neem (Mirabilis jalapa) leaf broth. Journal of Colloid and Interface Science 275(2)496-502.
  34. Silvestry-Rodriguez N, Sicairos-Ruelas EE, Gerba CP and Bright KR (2007). Copper as a disinfectant. Reviews of Environmental Contamination and Toxicology 191(1) 23-45.
  35. Strack. D., Vogt,T, Schliemann, W. (2003). Recent advances in betalain research. Phytochemistry, 62:247-269.
  36. Sun Y and Xia Y (2002). Shape controlled synthesis of gold and copper nanoparticles. Science 298(5601) 2176-2179.
  37. Tian J, Wong KK, Ho CM, Lok CN, Yu WY, Che CM, Chiu JF and Tam PK (2007). Topical delivery of silver nanoparticles promotes wound healing. ChemMedChem 2(1) 171-80.
  38. Tripathy A, Raichur AM, Chandrasekaran N, Prathna TC and Mukherjee A (2009). Process variables in biomimetic synthesis of silver nanoparticles by aqueous extract of Mirabilis jalapa flowers. Journal of Nanoparticle Research 12(1) 237-246.
  39. Wiley BJ, Im SH, Li ZY, Mclellan J, Siekkenen A and Xia Y (2006). Mane uvering the surface plasmon resonance of copper nanostructures through shape-controlled synthesis. Journal of Physical Chemistry B 110(32) 15666-15675.
  40. Yeo SY and Jeong SH (2003). Preparation and characterization of polypropylene/copper nanocomposite fibers. Polymer International 52(7)1053-1057.

International Journal of Scientific Research in Science and Technology

Downloads

Published

2020-08-30

Issue

Volume 7, Issue 4, July-August-2020

Section

Research Articles

License

Copyright (c) IJSRST

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
C R Rathi, S N Suresh, " Green Cellular Delivery of Copper Nanoparticle from Mirabilis Jalapa Flower Extract and Its Antipathogenic Activity, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 7, Issue 4, pp.255-263, July-August-2020. Available at doi : https://doi.org/10.32628/IJSRST207478