Calcium Signaling in Neurodegeneration : A Review

Authors

  • Rijul Mahesh Kharat  Hiranandani Foundation School Powai, Mumbai, Maharashtra, India

DOI:

https://doi.org/10.32628/IJSRST2296105

Keywords:

Calcium Signaling, Dysregulation of calcium, Alzheimer's disease, Parkinson's disease, Huntington's disease, Calcium Blockers

Abstract

Neurodegenerative disorders, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), and spinocerebellar ataxias (SCAs), pose a significant medical, social, financial, and scientific challenge. Recent data suggests that many of these illnesses have aberrant neuronal calcium (Ca2+) transmission. Normal aging causes alterations in neuronal Ca2+ signaling that are similar but less drastic. Here, we address the dysregulation of calcium in a number of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. Also noted is the potential effectiveness of Ca2+ blockers in the treatment of various illnesses.

References

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International Journal of Scientific Research in Science and Technology

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Published

2023-02-28

Issue

Volume 10, Issue 1, January-February-2023

Section

Research Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Rijul Mahesh Kharat "Calcium Signaling in Neurodegeneration : A Review" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 10, Issue 1, pp.113-120, January-February-2023. Available at doi : https://doi.org/10.32628/IJSRST2296105