Platelet Rich Plasma (PRP) Changing Facial Aesthetics

Authors

  • Jincy Nazar  Assistant Professor, Noorul Islam College of Dental Sciences, Pathamkallu, Kerala, India
  • Rony Mukkoottil Philip  Assistant Professor, Pushpagiri college of Dental Sciences, Thiruvalla, Kerala, India
  • Fathima Nehas  Post Graduate Student, Azeezia College of Dental Sciences and Research Centre, Adichanalloor, Kerala, India

DOI:

https://doi.org//10.32628/IJSRST52411138

Keywords:

Facial Aesthetics, Platelet-Rich Plasma

Abstract

This article provides a thorough examination of Platelet-Rich Plasma (PRP) therapy in the context of facial aesthetics. We delve into the scientific principles behind PRP, exploring its rich growth factor content and regenerative potential. The review encompasses a comprehensive analysis of recent studies and clinical trials, highlighting the efficacy of PRP in enhancing skin texture, reducing wrinkles, and promoting collagen synthesis. Furthermore, we discuss the procedural aspects of PRP application in facial aesthetics, including patient selection, preparation, and administration techniques. A critical evaluation of the safety profile and potential side effects is also presented, offering practitioners and patients valuable insights into the risk-benefit profile of PRP in facial rejuvenation and review of literature. The article concludes with a forward-looking perspective on emerging trends and future directions in PRP research for facial aesthetics. By synthesizing current knowledge and addressing key considerations, this review serves as a valuable resource for clinicians, researchers, and individuals interested in the evolving landscape of non-invasive facial enhancement modalities.

References

  1. Marx, R. E. (2001). Platelet-rich plasma: evidence to support its use. Journal of Oral and Maxillofacial Surgery, 59(3), 345-345.
  2. Sclafani, A. P., & McCormick, S. A. (2013). Induction of dermal collagenesis, angiogenesis, and adipogenesis in human skin by injection of platelet-rich fibrin matrix. Archives of Facial Plastic Surgery, 15(1), 1-8.
  3. Ferraro, G. A., De Francesco, F., Cataldo, C., Rossano, F., Nicoletti, G., & D'Andrea, F. (2017). PRP and Microfat in the treatment of facial lipoatrophy: our experience. In Aesthetic Plastic Surgery (Vol. 41, No. 3, pp. 669-679). Springer US.
  4. Kakudo, N., Minakata, T., Mitsui, T., Kushida, S., & Notodihardjo, F. Z. (2011). Proliferation-promoting effect of platelet-rich plasma on human adipose-derived stem cells and human dermal fibroblasts. Plastic and reconstructive surgery, 128(4), 492e-498e.
  5. Giordano, S., Romeo, M., Lankinen, P., & Di Summa, P. (2019). Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol. Cureus, 11(8), e5422.
  6. Ibrahim, Z. A., El-Ashmawy, A. A., Shora, H. A., & El-Tarhouny, S. A. (2016). Therapeutic efficacy and safety of combined autologous platelet-rich plasma with fractional ablative carbon dioxide laser resurfacing for treatment of facial atrophic acne scars. Journal of cosmetic dermatology, 15(4), 434-443.
  7. Anitua, E., Pino, A., & Jaén, P. (2016). Plasma rich in growth factors in the treatment of acute skin wounds. Wound Repair and Regeneration, 24(2), 204-212.
  8. Elnehrawy, N. Y., Ibrahim, Z. A., Eltoukhy, A. M., Eldorry, A. S., & Aboeldahab, S. (2017). Microneedling Plus Platelet-Rich Plasma Versus Microneedling Alone in the Treatment of Atrophic Post Acne Scars: A Split Face Comparative Study. Journal of cosmetic dermatology, 16(2), 223-228.
  9. Gkini, M. A., Kouskoukis, A. E., & Tripsianis, G. (2014). Rigorous comparative study of the efficacy of the Fraxel(®) and Quantum(®) lasers for skin rejuvenation. Laser therapy, 23(3), 175-184.
  10. B. L., Pietrzak, W. S., & Blanton, M. (2006). Platelet-rich plasma: a review of biology and applications in plastic surgery. Plastic and Reconstructive Surgery, 118(6), 147e-159e.
  11. Hesseler MJ, Shyam N. Platelet-rich plasma and its utilities in alopecia: a systematic review. Dermatol Surg. 2020;46(1):93–102. doi:10.1097/DSS.0000000000001965
  12. Redaelli, A., Romano, D., Marcianò, A., Face and Neck Revitalization with Platelet-Rich Plasma (PRP): Clinical Outcome in a Series of 23 Consecutive Patients. Journal of Drugs in Dermatology, 2010. 9(5): p. 466-472.
  13. Sundaram H, Mehta RC, Norine JA, Kircik L, Cook-Bolden FE, Atkin DH, et al. Topically applied physiologically balanced growth factors: A new paradigm of skin rejuvenation. J Drugs Dermatol. 2009;8((5 Suppl Skin Rejuenation)):4–13.
  14. Lei X, Xu P, Cheng B. Problems and solutions for platelet-rich plasma in facial rejuvenation: A systematic review. Aesthetic Plast Surg. 2019;43:457–69.
  15. Maisel-Campbell AL , Ismail A , Reynolds KA , et al. A systematic re- view of the safety and effectiveness of platelet-rich plasma (PRP) for skin aging. Arch Dermatol Res 2020;312:301–315 .
  16. Nanda S, Chauhan K, Shetty V, Dashore S, Bhatia S. Platelet-Rich Plasma in Aesthetics. Indian Dermatol Online J. 2021 Nov 25;12(Suppl 1):S41-S54. doi: 10.4103/idoj.idoj_290_21. PMID: 34976880; PMCID: PMC8664171.
  17. Goldstein S, Harley CB. in vitro studies of age-associated diseases. Fed Proc. 1979;38:1862–7.
  18. Vavken P, Saad FA, Murray MM. Age dependence of expression of growth factor receptors in porcine ACL fibroblasts. J Orthop Res. 2010;28:1107–12.
  19. Mori Y, Hatamochi A, Arakawa M, Ueki H. Reduced expression of mRNA for transforming growth factor beta (TGF beta) and TGF beta receptors I and II and decreased TGF beta binding to the receptors in in vitro-aged fibroblasts. Arch Dermatol Res. 1998;290:158–62.
  20. Elnehrawy NY, Ibrahim ZA, Eltoukhy AM, Nagy HM. Assessment of the efficacy and safety of single platelet-rich plasma injection on different types and grades of facial wrinkles. J Cosmet Dermatol. 2017;16(1):103–111.
  21. Lee ZH, Sinno S, Poudrier G et al. Platelet rich plasma for photodamaged skin: a pilot study. J Cosmet Dermatol. 2019;18(1):77–83.
  22. Oh IY, Kim BJ, Kim MN. Depressed facial scars successfully treated with autologous platelet-rich plasma and light-emitting diode phototherapy at 830 nm. Ann Dermatol. 2014;26:417–8.
  23. Kar BR, Raj C. Fractional CO2 laser vs fractional CO2 with topical platelet rich plasma in the treatment of acne scars: A split face comparison trial. J Cutan Aesthet Surg. 2017;10:136–44.
  24. Porwal S, Chahar YS, Singh PK. A comparative study of combined dermaroller and platelet-rich plasma versus dermaroller alone in acne scars and assessment of quality of life before and after treatment. Indian J Dermatol. 2018;63:403–8.
  25. R.C. Kelm and O. Ibrahim, Utility of platelet-rich plasma in aesthetics, Clinics in Dermatology, https://doi.org/10.1016/j. clindermatol.2021.08.007

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Published

2024-02-29

Issue

Section

Research Articles

How to Cite

[1]
Jincy Nazar, Rony Mukkoottil Philip, Fathima Nehas, " Platelet Rich Plasma (PRP) Changing Facial Aesthetics, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 11, Issue 1, pp.327-332, January-February-2024. Available at doi : https://doi.org/10.32628/IJSRST52411138