Synthesis, Characterization and Biological Evaluation of Novel Substitute 2,2'-(4,4'-((Phenylazanediyl)Bis(Methylene)) Bis (1h-1,2,3-Triazole-4,1-Diyl))Bis(N-(4-(3-Oxomorpholino) Phenyl)Acetamide) Via Click Chemistry Approach

Authors

  • H. P. Pandya  Shree D K V Arts & Science College, Jamnagar-361008 Gujarat, (India)
  • K. A. Joshi   Shree D K V Arts & Science College, Jamnagar-361008 Gujarat, (India)

Keywords:

Acetamide, Click, Chemistry, Biological, Activities, Fungal

Abstract

In current work we synthesized novel series of triazole derivatives of 2,2'-(4,4'- ((phenylazanediyl)bis(methylene)) bis (1H-1,2,3-triazole-4,1-diyl)) bis (N-(4-(3-oxomorpholino)phenyl)acetamide) via click chemistry approach in the presence DMF:H2O:n-BuOH, and CuSO4.5H2O of in good yield. The different studies indicate that newly synthesized novel compounds possess moderate to good biological activities. The title compounds have been synthesized with several structural variations biological evaluation of entirely synthesized compounds have been carried out in vitro for their antibacterial and antifungal efficacy against various bacterial and fungal strains. The structure of synthesized compounds characterized by their spectral (IR, 1H NMR and Mass) data. All compounds purity confirmed by TLC.

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International Journal of Scientific Research in Science and Technology

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Published

2021-04-30

Issue

Volume 8, Issue 2, March-April-2021

Section

Research Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
H. P. Pandya, K. A. Joshi "Synthesis, Characterization and Biological Evaluation of Novel Substitute 2,2'-(4,4'-((Phenylazanediyl)Bis(Methylene)) Bis (1h-1,2,3-Triazole-4,1-Diyl))Bis(N-(4-(3-Oxomorpholino) Phenyl)Acetamide) Via Click Chemistry Approach" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 8, Issue 2, pp.709-717, March-April-2021.