Larvicidal Effect of Seeds of Myristica Fragrans (Houttuyn) on Larvae of Anopheles Gambiae

Authors

  • Romanus Umoh  Department of Pharmacognosy and Natural Medicine, University of Uyo, Nigeria
  • Samuel Offor  Department of Pharmacognosy and Natural Medicine, University of Uyo, Nigeria
  • Nkechi Onyeukwu  Department of Pharmacology and Toxicology, University of Uyo, Nigeria
  • Akwaowo Elijah  Department of Biopharmacy and Clinical Pharmacy, University of Uyo, Nigeria
  • Hilary Otimanam  Department of Pharmacology and Toxicology, University of Uyo, Nigeria
  • Timma Uwah  Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Nigeria
  • Clement Jackson  Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Nigeria

Keywords:

Anopheles gambiae , Myristica fragrans, Larval toxicity, %mortality and  LC50

Abstract

The Larvicidal Activity of Methanol extract and fractions of Myristica fragrans (Myristicaceae) was evaluated on larvae of Anopheles gambiae. The seeds were macerated in 100% redistilled n-hexane for 24 hours to extract the oil, then in 100% redistilled methanol for 72hours, filtered and concentrated to dryness. The methanol crude extract of M. fragrans seeds exhibited % mortalities range of 30.00 + 0.00 -100+0.00 and LC50 of 0.02 mg/mL. N-hexane fraction of M. fragrans seeds was equally as active fraction with % mortalities range of 25+ 1.00-100+0.00 and LC50 of 0.02mg/mL. The reference compound Nicotine had %mortality range of 15.00+ 0.00 – 100.00+0.00 with LC50 of 0.04mg/mL.

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International Journal of Scientific Research in Science and Technology

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Published

2015-06-30

Issue

Volume 1, Issue 2, May-June-2015

Section

Research Articles

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How to Cite

[1]
Romanus Umoh, Samuel Offor, Nkechi Onyeukwu, Akwaowo Elijah, Hilary Otimanam, Timma Uwah, Clement Jackson "Larvicidal Effect of Seeds of Myristica Fragrans (Houttuyn) on Larvae of Anopheles Gambiae" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 1, Issue 2, pp.42-46, May-June-2015.