A Review on Anticancer Drug from Marine

Authors

  • Omkar A Patil  Rajarambapu College of Pharmacy, Kasegaon, Kasegaon, Walwa, Sangali, Maharashtra, India
  • Prajkta S Patil  Rajarambapu College of Pharmacy, Kasegaon, Kasegaon, Walwa, Sangali, Maharashtra, India
  • Trupti D Dudhgaonkar  Rajarambapu College of Pharmacy, Kasegaon, Kasegaon, Walwa, Sangali, Maharashtra, India
  • Shriniwas K Mohite  Rajarambapu College of Pharmacy, Kasegaon, Kasegaon, Walwa, Sangali, Maharashtra, India
  • Chandracanth S Magdum  Rajarambapu College of Pharmacy, Kasegaon, Kasegaon, Walwa, Sangali, Maharashtra, India

Keywords:

Marine Organisms, Bryostatin-1, Dolastation, Human Cancers

Abstract

The marine environment is a rich source of both biological and chemical diversity. It is very much likely that marine organisms would be wonderful source of biologically active molecules The collection of the marine therapeutics includes molecules with antibiotic, antiviral, antiphrastic, analgesic and anticancer agent from bacteria, cyanobacteria, tunica, fungi, sponge This reviewfocuses on the latest studies and critical research in this field and evidences the immense potential ofmarine organisms as sources of bioactive peptides and other anticancer biomolecules Various anticancer compounds like Aplidine, Bryostatin-1, Didemin B, Dolastation, Ecteinascidine with diverse modes of action, such as, anti-proliferative, antioxidant, anti-microtubule havebeen isolated from marine sources. Traditional chemotherapeutic agents have a range of side effects likefatigue, gastrointestinal distress and depression of immune system which introduces the these sources have been shown to have antioxidantactivity and cytotoxic effect on several human cancers such as leukemia, lymphoma, ovarian, melanoma, breast, bladder, neuroendocrine, prostatic, colon and non-small cell lung cancer very potently.

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International Journal of Scientific Research in Science and Technology

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Published

2016-08-30

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Volume 2, Issue 4, July-August-2016

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Research Articles

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[1]
Omkar A Patil, Prajkta S Patil,Trupti D Dudhgaonkar, Shriniwas K Mohite, Chandracanth S Magdum, " A Review on Anticancer Drug from Marine, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 2, Issue 4, pp.236-242, July-August-2016.