A Review On : Phytochemicals as Nutraceuticals

Authors

  • Prajakta S Patil  Rajarambapu College of Pharmacy, Kasegaon, Walwa, Sangali, Maharashtra, India
  • Kajal N Patil  Rajarambapu College of Pharmacy, Kasegaon, Walwa, Sangali, Maharashtra, India
  • Trupti D Dudhgaonkar  Rajarambapu College of Pharmacy, Kasegaon, Walwa, Sangali, Maharashtra, India
  • Shriniwas K Mohite  Rajarambapu College of Pharmacy, Kasegaon, Walwa, Sangali, Maharashtra, India
  • Chandrakant S Magdum  Rajarambapu College of Pharmacy, Kasegaon, Walwa, Sangali, Maharashtra, India

Keywords:

Nutraceuticals, Phytochemicals, Polyphenols, Flavonoids, Isoflavonoids

Abstract

Nutraceuticals are food product that provides health as well as medical benefits; including the prevention and treatment of disease. Few nutraceuticals are being used as pharmaceutical and a number of other being used and purchased by the general public as self-medication. Such products may range from dietary supplements to genetically engineered foods, herbal products and processed foods.

Phytochemicals of nutraceuticals importance are bioactive constituentsthat sustain or promote health and occurs at the intersection of food andpharmaceutical industries. Such substances may range from isolatednutrients, dietary supplements and specific diets to geneticallyengineered designer foods, herbal products, processed foods andbeverages. Phytochemicals are broadly described as polyphenols,flavonoids, isoflavonoids, anthocyanidins, terpenoids etc,. Theyhave tremendous impact on the health care system and mayprovidemedical health benefits including the prevention and/ or treatment ofdiseases and physiological disorders. Majority of foods, such as wholegrains, beans, fruits, vegetables and herbs contain phytochemicals.Amongst these, fruits and vegetables contribute to the significantsources of phytochemicals. These phytochemicals, either alone and/orin combination, have tremendous therapeutic potential in curing variousailments. The respective health benefits are based on science andethics, for health claims, for functional foods, and presence of certainphytochemicals. They play certain pharmacological effects in humanhealth as antioxidants, antibacterial, antifungal, anti-inflammatory, antiallergic,antispasmodic, chemopreventive, hepatoprotective,hypolipidemic, neuroprotective, hypotensive, prevent aging, diabetes,osteoporosis, DNA damage, cancer and heart diseases, induceapoptosis, diuretic, CNS stimulant, analgesic, protects from UV inducedcarcinogenesis, prevent, immuno-modulator and carminative.

References

  1. Biesalski HK. Nutraceuticals: the link between nutrition andmedicine. In: Kramer K, Hoppe PP, Packer L. (eds) Nutraceuticalsin health and disease prevention. New York: Marcel Deckker Inc.2001, pp. 1-26.
  2. Kalra EK. Nutraceutical - Definition and Introduction. AAPSPharmSci 2003; 5: 1-2
  3. Prakash D, Dhakarey R, Mishra A. Carotenoids: the phytochemicals of nutraceutical importance. Ind J Agric Biochem2004; 17: 1-8.
  4. Cindy S. Oliveri, Nutraceuticals,Phytochemicals, and Antioxidants-What AreThey All About, OSU Extension Fact Sheet,2003, 5051-5098.
  5. Lockwood Brain, Nutraceuticals, secondedition, Pharmaceutical press. London, 2007, 60-65.
  6. Scalbert A, Manach C, Morand C and Remesy C. Dietarypolyphenols and the prevention of diseases. Critical Rev Food SciNutr 2005; 45, 287-306.
  7. Kris-Etherton P, Hecker K, Bonanome A, Coval S, BinkoskiA,Hilpert K. Bioactive compounds in foods: their role in theprevention of cardiovascular disease and cancer. Am J Med 2002;113, 71S–88S.
  8. Cieślik E, Greda A, Adamus W. Contents of polyphenols in fruitsand vegetables. Food Chem 2006; 94, 135-142.9. Kondratyuk TP, Pezzuto JM. Natural Product Polyphenols ofRelevance to Human Health. Pharm Biol 2004; 42, 46-63
  9. Fisher C, Scott TR., Food flavours: biologyand chemistry. Cambridge, U.K.: The Royal Society of Chemistry, 176 p. (1997).
  10. Crozier A, Clifford M, Ashihara H., Plantsecondary metabolites: occurrence structure and role in the human diet. Oxford, U.K.:Blackwell Publishing Ltd., 384 p. (2006).
  11. Das S, Tyagi AK, Kaur H., Cancer modulationbyglucosinolates: a review. Curr. Sci. 79(12):1665–71, (2000).
  12. Kozukue N, Han JS, Lee KR, Friedman M.,Dehydrotomatine and -tomatine content in tomato fruits and vegetative plant tissues. J.Agric. Food Chem., 52:2079–83, (2004).
  13. Prior RL, Cao G., Antioxidant phytochemicalsin fruits and vegetables; diet and health implications. Hort. Science, 35(4):588–92,(2000).
  14. Brower V. Nutraceuticals: poised for a healthy slice of the healthcare market? Nat Biotechnol, 16, 1998, 728-731.
  15. Cindy S. Oliveri, Nutraceuticals, Phytochemicals, and Antioxidants-What AreThey All About, OSU Extension Fact Sheet, 2003, 5051-5098.
  16. Lockwood. Brain, Nutraceuticals, second edition, Pharmaceutical press. London, 2007, 60-65.
  17. Kalra EK. Nutraceutical--definition and introduction. AAPS Pharm Sci, 5, 2003, 27-28

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Published

2016-04-30

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Section

Research Articles

How to Cite

[1]
Prajakta S Patil, Kajal N Patil, Trupti D Dudhgaonkar, Shriniwas K Mohite, Chandrakant S Magdum, " A Review On : Phytochemicals as Nutraceuticals, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 2, Issue 2, pp.254-260, March-April-2016.