Multicomponent One-Pot Synthesis and Biological Evaluation of Pyrano[2,3-C] Pyrazoles
Keywords:
Pyrazoles, Biological Evaluation, One-Pot Synthesis, MCRs, TLC, MeOHAbstract
Despite recent advances in molecular biology and the progress in combinatorial synthetic methodology, the rate of introduction of new medicines has decreased markedly over the past two decades [1]. Structural diversity in a focused collection of potential therapeutics is believed to increase the positive hit rate. Most medicines in use are still small synthetic organic molecules that often contain a heterocyclic ring.
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