Synthesis and Antimicrobial Screening of Metal Complexes of 1-(5-Chloro-2-Hydroxyphenyl)-3-(2,4-Dichlorophenyl) Propane-1,3-Dione

Authors

  • D. D. Suryawanshi  Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India
  • A. D. Suryawanshi  Department of Physics, B. J. College Ale.,Pune, Maharashtra, India
  • A. S. Padampalle  Department of Physics, S. C. S. College Omerga.,Osmanabad, India
  • A. S. Rajbhoj  Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India

Keywords:

Baker-Venkatraman rearrangement, metal complexes, XRD, thermal study.

Abstract

1-(5-Chloro-2-Hydroxyphenyl)-3-(2,4-Dichlorophenyl) Propane-1,3-Dione and its metal complexes have been synthesized by conventional method. The diketone is offered by employing Baker- Venkatraman rearrangement. The synthesized compounds were confirmed by the spectroscopic analysis such as UV, IR , 1H-NMR, 13C-NMR, mass, elemental analysis, magnetic susceptibility, XRD and evaluated for antibacterial screening.

References

  1. M. Thiyagarajan, S.S. Sharma, Life Sci., 74, (2004), 969.
  2. T. Dziemboska, Z. Rozwadowski, Curr. Org. Chem, 5, (2001), 289.
  3. S. Antony, R. Kuttan, G. Kuttan, Immun. Invest, (1999), 28, 291.
  4. V. Fargeas, M. Baglouch, E. Muley, J. Baffreau, D. Mehard, P. Gosselin, J. P. Berge, C. Barthomeuf, Tetrahedron, 60, (2004), 1035
  5. J. Christoffers, H. Oertling, P. Fisher, W. Frey, Tetrahedron, 59, (2003), 3769
  6. A. R. Katritzki, Z. Wang, M. Wang, C. R. Wilkinson, D. Hall, N. G. Akhmedor, J. Org. Chem, 69, (2004), 6617
  7. D. Pokormy, W. Striner, D. W. Ribbons, Biotechnol, 15, (1997), 291
  8. G. Grogan, J. Mol. Catal. B. Enzyme, 19, (2002), 73
  9. A. Siedle in comprehensive Coordination Chem., 1987, Wilkinson, pergamon press, Oxford, vol. 2 cha 15,4 pp365.
  10. T. Nishiyama, S. Shiotsu, T Polym. Degrad & Stab, 2002, 76, 435-439.
  11. S. T. Heller, S. R. Natrajan, Org. Lett. 2006, 8, 2675.
  12. D. Simoni, F. Invidita, R. Rondanin, S. Grimaudo, G. Cannizzo, E. Barbusca, F. Porretto, N. Alessandro and M. Tolomeo, J Med Chem., 1999, 42, 4961.
  13. V. V. Alekseev, K. N. Zelenin and S. I. Yakimovich, Russ J Org Chem., PO1995, 31, 868.
  14. R Kumar and C. Y. Joshi, Arkivoc, 2007, 9, 142.
  15. O Kuzueva, Y Burgart, V Saloutin and O Chupakhin, Chemistry of Heterocyclic compounds, 2001, 37, 1130.
  16. N Acton, A Brossi, D L Newton and M B Sporn, J Med Chem., 1980, 23, 805-809.
  17. G Crouse, M McGowan and R Boisvenue, J Med Chem., 1989, 32, 2148.??????????????????????????? ?????????????????????????????????????????????????I Bennett, NJ Broom, R Cassels, J S Elder, N D Masson and O’ Hanlon P L, Nioorg Med Chem Lett., 1999, 9, 1847-1852.Chate A. V. Bhagat S. S. and Gill C. H., J. Heterocyclic Chem, 2011, DOII. 1002/955.I Andrae, A Bringhen, F Bohm, H Gonzenbach, T Hill, Mulroy L and T G Truscott, J Photochem Photobiol B: Biol., 1997, 37, 147-150.A. V. Chate , R. Joshi, P. Mandhane, C. H. Gill, J. Korean Chemikcal Soci. 2011, 55, 4.
  18. A. V. Chate, R. S. Joshi, V. Badadhe and C. H. Gill, Bull. Korean Chem. Soc, 2011, vol.32, no. 11, 3887.
  19. Carvajal J. R, Roisnel T, Winplotr, A graphic tool for powder diffraction, Laboratoire Leon Brillouin (ceal/cnrs) 91191 Gif sur Yvette Cedex, France, 2004.
  20. Shoemaker D. P., Garland C.W., Experiments in Physical Chemistry, 5th ed., McGraw-Hill International Edition, New York, 1989.
  21. Deshmukh M. B, S. Dhongade-Desai, Chavan S. S, Indian J. Chem. 44 (2005) 1659.
  22. J. Sestak, V. Satava, W. W. Wendland, Therm. Chem. Acta, 7, (1973), 333.
  23. J. T. Makodi, A. S. Aswar, J. Indian Chem Soc, 80 (1), 2003,44.
  24. Sharma O, Singla R, Shrivastava B, Bhat V, Shenoy G, Sreenivasan K, Indo Globl J. of Pharmaceutical Sciences; 2012; 2(1), 70-75.

International Journal of Scientific Research in Science and Technology

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Published

2017-12-15

Issue

Volume 3, Issue 9, November-December-2017

Section

Research Articles

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[1]
D. D. Suryawanshi, A. D. Suryawanshi, A. S. Padampalle, A. S. Rajbhoj "Synthesis and Antimicrobial Screening of Metal Complexes of 1-(5-Chloro-2-Hydroxyphenyl)-3-(2,4-Dichlorophenyl) Propane-1,3-Dione" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 3, Issue 9, pp.75-78, November-December-2017.