Synthesis and Antibacterial Activity of Novel 3-Hydroxy Benzoic Acid Hybrid Derivative [Part I]

Authors

  • Maruti S. Satpute  Department of Chemistry, R. D. National College and W. A. Science College, Linking Road, Bandra (W), Mumbai, Maharashtra, India
  • Vijay D. Gangan  Department of Chemistry, Loba R & D Centre, Loba Chemie Pvt. Ltd., Plot No. D - 22, Tarapur MIDC, Boisar, Palghar, Maharashtra, India
  • Indu Shastri  Department of Chemistry, R. D. National College and W. A. Science College, Linking Road, Bandra (W), Mumbai, Maharashtra, India

DOI:

https://doi.org//10.32628/IJSRST18401159

Keywords:

3-Hydroxy Benzoic Acid, IR, 1HNMR, TOF MS, DCC, DMAP, Biological Activities Antibacterial, Ditch-Plate Method.

Abstract

3-hydroxy benzoic acid is an organic chemical which can be obtained naturally as well as synthetically. The literature survey reveals its various biological properties viz. antimicrobial, antialgal, antimutagenic, antiestrogenic, hypoglycemic, anti-inflammatory, anti-platelet aggregating, nematicidal, antiviral, antioxidant etc. It is also reported to be used as preservative in many drugs, cosmetic products, pharmaceuticals, food and beverages. Some derivatives of 3-hydroxybenzoic acid are found to possess direct action on Hbs molecules, inhibit acetic acid induced oedema and used in management of sickle cell disease. It is also has wide applications in perfumery industries. In this paper, novel ester / hybrid derivative of 3- Hydroxy benzoic acid was synthesized and tested for its potential antibacterial activity. This combinatorial synthesis of novel 3-Hydroxy benzoic ester / hybrid derivative can be a useful approach to generate potent chemotherapeutic agents in developing new drug candidates.

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International Journal of Scientific Research in Science and Technology

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Published

2018-12-30

Issue

Volume 4, Issue 11, November-December-2018

Section

Research Articles

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How to Cite

[1]
Maruti S. Satpute, Vijay D. Gangan, Indu Shastri, " Synthesis and Antibacterial Activity of Novel 3-Hydroxy Benzoic Acid Hybrid Derivative [Part I], International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 4, Issue 11, pp.369-374, November-December-2018. Available at doi : https://doi.org/10.32628/IJSRST18401159