An Amperometric Sensor for the Determination of Dopamine Using Poly Zincon Film Modified Electrode
Keywords:
Poly Zincon Film modified electrode, Dopamine, Amperometric sensorAbstract
Zincon, a metal ion indicator, has been polymerised on the graphite electrode to get a poly zincon film modified electrode. The formation of the polymer film (PZF)was confirmed by optical microscopis studies. The PZF modified electrode was characterised by the cyclic voltammetry, square wave voltammetry and chronoamperometry. The experimental parameters influencing the electrochemical behaviour of the PZF modified electrode such as pH and scan rates in presence of dopamine were optimised. The modified electrode showed excellent sensitivity and stability towards the electrocatalytic oxidation of dopamine. The determination range for dopamine was found to be 1.16 to 401µM with a correlation coefficient (R2) of 0.997. The limit of detection for the determination of Dopamine was 0.38 µM. The proposed method was used for the determination of dopamine in pharmaceutical preparations.
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