Synthesis, Characterization & Antimicrobial Activity of Some New Dihydropyridine Derivatives Derived From 3-Aryl-2-Isobutanoyl-N-Phenyl-Acrylamide

Authors

  • D. N. Joshi  Department of Chemistry, R. R. Mehta college of Science & C.L.Parikh College of Commerce Palanpur, Gujarat, India

Keywords:

3-Aryl-2-isobutanoyl-N-phenyl-acrylamide, Pyrazoles, Antimicrobial activities.

Abstract

1,4-Dihydropyridine is the significant subclass of pyridines, the best known heterocyclic compounds which are associated with good number of pharmacological activities. 1,4-Dihydropyridines whether symmetrical or asymmetrical are expected for their cardiovascular and other pharmacological properties. Some new 4-Aryl-2,6-diisopropyl-3,5-bis[N-phenyl-aminocarbonyl]-1,4-dihydropyridines.The Dihydropyridine derivatives of Type (1a-j) have been synthesized by the condensation of 3- Aryl-2-isobutanoyl-N-phenyl-acrylamide and 4-Methyl-3-oxo-N-phenyl-pentanamide and ammonia. All the prepared compounds were characterized by their spectral (I.R., N.M.R., Mass) data and screened for their antimicrobial activities

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International Journal of Scientific Research in Science and Technology

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Published

2015-07-30

Issue

Volume 1, Issue 3, July-August-2015

Section

Research Articles

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How to Cite

[1]
D. N. Joshi "Synthesis, Characterization & Antimicrobial Activity of Some New Dihydropyridine Derivatives Derived From 3-Aryl-2-Isobutanoyl-N-Phenyl-Acrylamide " International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 1, Issue 3, pp.192-195, July-August-2015.