Hypoglycemic Activity Of Ethanolic Extract of Aloe Vera In Control And Diabetic Mice

Authors

  • J. S. Kadam  P.G. Department of Zoology, Sadguru Gadage Maharaj College, Karad, Maharashtra, India
  • R. N. Patil  P.G. Department of Zoology, Sadguru Gadage Maharaj College, Karad, Maharashtra, India

Keywords:

Aloe Vera, Hypoglycemia, Intraperitoneal Diabetes Mellitus, Alloxan

Abstract

Herbal medicines are frequently considered to be less toxic and have fewer side effects than synthetic ones. Hence, the present study was designed to evaluate hypoglycemic activity of Aloe vera. Diabetes mellitus was induced by single intraperitoneal injection of alloxan 120 mg/kg body weight. Ethanolic extract of Aloe vera was administered intraperitoneally 300mg/kg body weight in diabetic mice. The treatment effects were compared with standard antidiabetic drugs insulin 1IU/kg body weight. A significant decrease in blood glucose level and improvement in the body weight was observed. The observed hypoglycemic activity could be associated with the phytochemicals present in this plant extract. Therefore, the result suggests that Aloe vera leaf extract is potent hypoglycemic agent.

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International Journal of Scientific Research in Science and Technology

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Published

2018-02-03

Issue

Volume 5, Issue 2, January-February-2018

Section

Research Articles

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How to Cite

[1]
J. S. Kadam, R. N. Patil, " Hypoglycemic Activity Of Ethanolic Extract of Aloe Vera In Control And Diabetic Mice, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 5, Issue 2, pp.47-51, January-February-2018.