Phytochemistry of Nerium Oleander L. Root

Authors

  • Keshav K. Deshmukh  Principal, Department of Chemistry, S. N. Art's, D. J. Malpani Commerce and B. N. Sarada Science College, Sangamner, Ahmednagar, Maharashtra, India
  • Goraksh J. Hase  Research Scholar, Department of Chemistry, S. N. Art's, D. J. Malpani Commerce and B. N. Sarada Science College, Sangamner, Ahmednagar, Maharashtra, India

Keywords:

Nerium Oleander L., alkaloids, trerepenoid.

Abstract

The present study revealed that, In Nerium Oleander L.  plant roots  are present bioactive phytoconstituents. In Apocyanace family of plant majority contains alkaloids and terepenoids. Extraction of phytoconstituents done by hot extraction method using soxhlet apparatus. The methanol extract have 18.20 % extractive value after successive extraction in n-hexane, chloroform, ethyl acetate extractive value 4.01 %, 6.12% and 9.35% respectively. The Brown colored root contains other minor phytoconstituents are stereoid, saponins, polar glycosides, carbohydrates and phenolic compounds. The phytochemical tests are performed for to finding bioactive secondary metabolic compounds. Plant have been reported many pharmaceutical activities such as antibacterial, antifungal, cytotoxic, antitumor activity.

References

  1. Garima Zibbu and Amla Batra, A Review on Chemistry and Pharmacological activity of Nerium oleander L, Lab No: 5, Biotech lab, Department of Botany, University of Rajasthan, Jaipur, J. Chem. Pharm. Res., 2010, 2(6):351-358.
  2. Hougen, T. J; Lloyd, B. L; Smith, T. W (1979), "Effects of inotropic and arrhythmogenic digoxin doses and of digoxin-specific antibody on myocardial monovalent cation transport in the dog". Circulation Research. 44 (1): 23–31.
  3. Pao?Franco, Amaris; Hammond, Tara N.; Weatherton, Linda K.; DeClementi, Camille; Forney, Scott D. (29 July 2017). "Successful use of digoxin?specific immune Fab in the treatment of severe Nerium oleander toxicosis in a dog". Journal of Vererinary Emergency and Critical Care. 27 (5): 596–604. 
  4. Langford, Shannon D; Boor, Paul J (1996). "Oleander toxicity: An examination of human and animal toxic exposures". Toxicology. 109 (1): 1-13.
  5. Herrera, Javier (1991). "The reproductive biology of a riparian Mediterranean shrub, Nerium oleander L. (Apocynaceae)". Botanical Journal of the Linnean Society. 106 (2): 147-72. 
  6. Chandrashekar Kodangala, Santanu Saha and Prasanna Kodangala, Phytochemical studies of aerial parts of the plant Leucas lavandulaefolia, Der Pharma Chemica, ISSN 0975-413X, 2010, 2(5):434-437.
  7. Anonymous, Wealth of India, NISC publishing company, New Delhi, 1961, 79.
  8. K.R.Kirtikar .and B.D.Basu, Indian Medicinal Plants, 2nd Ed., Periodic Experts Book Agency, New Delhi, 1975, 2020.
  9. K.M.Nadakarni, Indian Material Medica, Popular prakashan, Bombay, 1992, 739. [4] J.E.Smith, Acta Pharma Indoneshia, 110, 1985, 27.
  10. K.S.Chandrashekar, A.B.Joshi, D.Satyanarayana, E.V.S. Subramanyam, Indian Journal of Chemistry, 45B, 2006, 1968.
  11. K.S.Chandrashekar, K.S.Prasanna. Der Pharma Chemica, 2(4), 2010, 21 [7] D.A. Johonsen, “Plant microtechnique”, New York,1940,182

International Journal of Scientific Research in Science and Technology

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Published

2019-01-04

Issue

Volume 5, Issue 4, January-2019

Section

Research Articles

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How to Cite

[1]
Keshav K. Deshmukh, Goraksh J. Hase, " Phytochemistry of Nerium Oleander L. Root, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 5, Issue 4, pp.23-26, January-2019.