Association of Cardiovascular Complications in Potassium Disorders with Cardiovascular Disease, Diabetes Mellitus and Chronic Kidney Disease

Authors

  • Siddhartha Sawadekar  Department of Clinical Pharmacy Practices, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dist. Dhule, Maharashtra, India
  • Someshwar Moholkar  Department of Clinical Pharmacy Practices, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dist. Dhule, Maharashtra, India

Keywords:

Cardiovascular Complications, Potassium Disorders, Cardiovascular Disease, Diabetes Mellitus, Chronic Kidney Disease

Abstract

Potassium disorders are common in patients with cardiovascular disease, chronic kidney disease, and diabetes mellitus. Hypokalemia and hyperkalemia are important electrolyte abnormalities that have generally been defined based on serum potassium concentrations develop with impaired renal function, and individuals with diabetes mellitus and chronic kidney disease are at greatest risk, as both may contribute to the development of the serious cardiovascular disease. Potassium concentrations have been associated with a higher risk of atrial fibrillation, ventricular fibrillation, hypertension and risk for arrhythmia. Hypokalemia is defined based on serum potassium concentrations <3.5 mEq/L is a risk factor of atrial fibrillation, while ventricular fibrillation, and sudden cardiac death. Hyperkalemia is defined based on serum potassium concentrations >6.0 mEq/L is the show effect of bradycardia, asystole. Potassium is important for the primary ion mediating cardiac repolarization in the hypokalemic condition they produce the effects of myocardial refractory periods and increases the risk for arrhythmia condition. And hyperkalemia causes slowed conduction and sometimes block conduction effect on the progressive result in asystole. The kidney maintaining the body potassium. In the case of chronic kidney disease, the capacity to maintain potassium level in the body is facing the alterations and the result is a problematic condition for transcellular electrolyte shifts. This condition increases the risk for hyperkalemia or hypokalemia and associated problems. Potassium abnormalities are one of the important reasons for electrolyte imbalances seen in DKA and risk factors for fatal arrhythmia. This condition increases the risk for hyperkalemia or hypokalemia and associated problems. We are studying the cardiovascular risk association between a serum potassium level and cardiovascular disease, chronic kidney disease, diabetes mellitus conditions.

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International Journal of Scientific Research in Science and Technology

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Published

2020-04-30

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Volume 7, Issue 2, March-April-2020

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Research Articles

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[1]
Siddhartha Sawadekar, Someshwar Moholkar, " Association of Cardiovascular Complications in Potassium Disorders with Cardiovascular Disease, Diabetes Mellitus and Chronic Kidney Disease, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 7, Issue 2, pp.391-400, March-April-2020.