Evaluation of Phytochemicals and Antioxidant potential of aqueous extract of Myristica fragrans

Authors

  • Malarvizhi V  Assistant Professor, Department of Biochemistry, Rabiammal Ahamed Maideen college for women, thiruvarur, Tamilnadu, India
  • Jenni. P  PG Scholar, Department of Biochemistry, Rabiammal Ahamed Maideen college for women, Thiruvarur, Tamilnadu, India

DOI:

https://doi.org//10.32628/IJSRST207361

Keywords:

Myristica fragrans, antioxidant activity, secondary metabolites and free radicals

Abstract

Antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable molecules that the body produces as a reaction to environmental and other pressures. Antioxidants act as radical scavenger, hydrogen donor, electron donor, peroxide decomposer, singlet oxygen quencher, enzyme inhibitor, synergist, and metal-chelating agents. The damage caused by antioxidants has been linked to cancer, atherosclerosis, and vision loss. Need of antioxidant with less side effects emerges nowadays. In this present qualitative evaluation shows this plant contains secondary metabolites like terpenoids, flavanoids, saponins, tannins, alkaloid, steroid, glycosides, proteins and coumarins. Myristica fragrans have been reported for its versatile antioxidant activity.

References

  1. Dillard CG AT, Charleux JL, Crozier-Willi G. Functional food science and defence against reactive oxygen species. British Journal of Nutrition; 1998, 80(1): S77-S112.
  2. Haraguchi H, Ishikawa H, Kubo I. Antioxidative action of diterpenoids from Podocarpusnagi. PlantaMedica; 1997, 63: 213–215.
  3. Jaiswal P, Kumar P, Singh VK, Singh DK. Biological Effects of Myristica  fragrans 2011
  4. Knight JA. Review: Free Radicals, Antioxidants, and the Immune System. Annals of Clinical & Laboratory Science; 2000, 30(2).
  5. Kurutas EB. The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state. Kurutas Nutrition Journal; 2016, 15(71).
  6. Phytochemicals content, antioxidant and hypoglycaemic activities of commercial 2016 nutmeg mace (Myristica fragrans L.) and pimento (Pimenta dioica (L.) Merr.) Monica Rosa Loizzo  Vincenzo Sicari Maria Concetta Tenuta  June 2017, Volume 24, Issue 17, pp 14758–14769
  7. Senthilkumar Balakrishnan Ilakkia Sivaji Selvam Kandasamy Biosynthesis of silver nanoparticles using Myristica fragrans seed (nutmeg) extract and its antibacterial activity against multidrug-resistant (MDR) Salmonella enterica serovar Typhi isolates 2010, 4(8): 118-126.
  8. Sherwin E.R, Branen R, Dekker M. Antioxidants In Food Additives. New York; 1990, 139–193.
  9. Sherwin E.R, Branen R, Dekker M. Antioxidants In Food Additives. New York; 1990, 139–193.
  10. Sindhi V, Gupta V, Sharma K, Bhatnagar S, Kumari R, Dhaka N. Potential applications of antioxidants – A review. Journal of Pharmacy Research; 2013, 7(9): 828-835.
  11. Singh A, Thakur Bais R. Evaluation of bioactive compounds in different extracts of Myristica fragrans and their antioxidant potential. International Journal of Biology Research; 2018, 3(1): 52-56.
  12. Suchandra Chatterjeea ZareenaNiaza S.Gautama Soumyakanti Adhikarib Prasad  S.Variyara ArunSharmaa Antioxidant activity of some phenolic constituents from green pepper (Piper nigrumL.) and fresh nutmeg mace (Myristica fragrans) 2017, 52: 116- 119
  13. Thomas RA, Krishnakumari S. Phytochemical profiling of myristica fragrans seed extract with different organic solvents. Asian J Pharm Clin Res; 2015, 8(1): 303-307.
  14. Tripathi R, Mohan H, Kamat JP. Modulation of oxidative damage by natural products.
  15. Veeru P, Pankaj Kishor M, Meenakshi M. Screening of medicinal plant extracts for antioxidant activity. Journal of Medicinal Plants Research; 2009, 3(8): 608-612.
  16. Vipin Kumar Bansalb VikashBabuc NishiMaithilaChemistry, antioxidant and antimicrobial potential of nutmeg (Myristica fragrans Houtt) 2013 Vanshika Adiani Sumit Gupta Suchandra Chatterjee Activity guided characterization of antioxidant components from essential oil of Nutmeg (Myristica fragrans) 2015 14(2): 94–101.
  17. Huang DJ, Ou BX, Prior RL. The chemistry behind antioxidant capacity assays. J Agric Food Chem; 2005, 53: 1841-1856.
  18. Hudson B.J.F. Food Antioxidants Elsevier: Amsterdam The Netherlands. 1991.
  19. Iyer RI, Jayaraman G, Ramesh A. In vitro responses and production of phytochemicals of potential medicinal value in nutmeg Myristica fragrans Houtt. Indian Journal of Science and Technology; 2009, 2(4 J Pharm Res; 2008, 7: 1089–99.
  20. Jaiswal P, Kumar P, Singh VK, Singh DK. Biological Effects of Myristica  fragrans.
  21. Jukic M, Potiteo O, Milos M. Chemical composition and antioxidant effect of free volatile aglycones from nutmeg (Myristica fragransHoutt.) compared to its essential oil. Crotica Chemical Acta; 2006, 79(2): 09–214.
  22. Kanta Sahu R, Kar M, Routray R. DPPH Free Radical Scavenging Activity of Some Leafy Vegetables used by Tribals of Odisha, India. Journal of Medicinal Plants Studies; 2013, 1(4): 21-27.
  23. Kanwar JR, Kanwar RK, Burrow H, Baratchi S. Recent advances on the roles of NO in cancer and chronic inflammatory disorders. Curr Med Chem; 2009, 16: 2373–2394.
  24. Kattappagari KK, Teja CSR, Kommalapati RK, Poosarla C, Gontu SR, Ramana Reddy BV. Role of antioxidants in facilitating the body functions: A review. Journal of orofacial sciences; 2015, 7(2): 71-75.
  25. Knight JA. Review: Free Radicals, Antioxidants, and the Immune System. Annals of Clinical & Laboratory Science; 2000, 30(2).
  26. Kurutas EB. The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state. Kurutas Nutrition Journal; 2016, 15(71).
  27. Latha PG, Sindhu PG, Suja SR, Geetha BS, Pushpangadan P, Rajasekharan S. Pharmacology and chemistry of Myristica fragrans Houtt. a review. Journal of Spices and Aromatic Crops; 2005, 14(2): 94–101.

International Journal of Scientific Research in Science and Technology

Downloads

Published

2020-06-30

Issue

Volume 7, Issue 3, May-June-2020

Section

Research Articles

License

Copyright (c) IJSRST

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Malarvizhi V, Jenni. P, " Evaluation of Phytochemicals and Antioxidant potential of aqueous extract of Myristica fragrans, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 7, Issue 3, pp.352-356, May-June-2020. Available at doi : https://doi.org/10.32628/IJSRST207361